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Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study - PubMed

Randomized Controlled Trial

Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study

Marja Michelin Guerra et al. Braz J Otorhinolaryngol. 2008 May-Jun.

Abstract

Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population.

Aim: to study the impact of amoxicillin for 7 days in post-adenotonsillectomy recovery, comparing results with a control group.

Study type: prospective, randomized, controlled study with 120 patients.

Patients and methods: the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities.

Results: It was only in the fourth post-operative day that the group receiving antibiotic agents showed a statistically significant difference as far as pain is concerned. There was no difference between the two groups for other data analyzed.

Conclusion: considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.

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Figures

Figure 1
Figure 1

PAIN - Comparative chart - prevalence of pain between groups

Figure 2
Figure 2

USE OF DIPYRONE TO MANAGE PAIN - GROUP 1 - 79% of the patients in group 1 required analgesia with dipyrone. Analgesics were mostly required by the second day of post-op and were administered to 23.3% of the patients

Figure 3
Figure 3

USE OF DIPYRONE TO MANAGE PAIN - GROUP 2 - 88% of the patients in group 2 required analgesics to manage their pain. Analgesics were mostly required by the third day of post-op and were administered to 21% of the patients.

Figure 4
Figure 4

FEVER IN THE GROUP TREATED WITH ANTIBIOTICS - twenty-two patients (51.2%) in group 1 had fever in the post-op.

Figure 5
Figure 5

FEVER IN THE CONTROL GROUP - 26.9 patients (51.9%) in group 2 had fever in the post-op.

Figure 6
Figure 6

BLEEDING - incidence of post-op bleeding in the groups. No cases of primary bleeding were reported.

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