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Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes - PubMed

  • Urinary angiotensinogen is correlated with blood pressure in men (Bogalusa Heart Study).

    Kobori H, Urushihara M, Xu JH, Berenson GS, Navar LG. Kobori H, et al. J Hypertens. 2010 Jul;28(7):1422-8. doi: 10.1097/HJH.0b013e3283392673. J Hypertens. 2010. PMID: 20375906 Free PMC article.

  • Blood pressure loci identified with a gene-centric array.

    Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I, O'Brien ET, Poulter NR, Sever P, Shields DC, Thom S, Wannamethee SG, Whincup PH, Brown MJ, Connell JM, Dobson RJ, Howard PJ, Mein CA, Onipinla A, Shaw-Hawkins S, Zhang Y, Davey Smith G, Day IN, Lawlor DA, Goodall AH; Cardiogenics Consortium; Fowkes FG, Abecasis GR, Elliott P, Gateva V; Global BPgen Consortium; Braund PS, Burton PR, Nelson CP, Tobin MD, van der Harst P, Glorioso N, Neuvrith H, Salvi E, Staessen JA, Stucchi A, Devos N, Jeunemaitre X, Plouin PF, Tichet J, Juhanson P, Org E, Putku M, Sõber S, Veldre G, Viigimaa M, Levinsson A, Rosengren A, Thelle DS, Hastie CE, Hedner T, Lee WK, Melander O, Wahlstrand B, Hardy R, Wong A, Cooper JA, Palmen J, Chen L, Stewart AF, Wells GA, Westra HJ, Wolfs MG, Clarke R, Franzosi MG, Goel A, Hamsten A, Lathrop M, Peden JF, Seedorf U, Watkins H, Ouwehand WH, Sambrook J, Stephens J, Casas JP, Drenos F, Holmes MV, Kivimaki M, Shah S, Shah T, Talmud PJ, Whittaker J, Wallace C, Delles C, Laan M, Kuh D, Humphries SE, Nyberg F, Cusi D, Roberts R, Newton-Cheh C, Franke L, Stanton AV, Dominiczak AF, Farrall M, Hingorani AD, Samani NJ, Caulfield MJ, Mu… See abstract for full author list ➔ Johnson T, et al. Am J Hum Genet. 2011 Dec 9;89(6):688-700. doi: 10.1016/j.ajhg.2011.10.013. Epub 2011 Nov 17. Am J Hum Genet. 2011. PMID: 22100073 Free PMC article.

  • Hypercontrols in genotype-phenotype analysis reveal ancestral haplotypes associated with essential hypertension.

    Balam-Ortiz E, Esquivel-Villarreal A, Huerta-Hernandez D, Fernandez-Lopez JC, Alfaro-Ruiz L, Muñoz-Monroy O, Gutierrez R, Figueroa-Genis E, Carrillo K, Elizalde A, Hidalgo A, Rodriguez M, Urushihara M, Kobori H, Jimenez-Sanchez G. Balam-Ortiz E, et al. Hypertension. 2012 Apr;59(4):847-53. doi: 10.1161/HYPERTENSIONAHA.111.176453. Epub 2012 Feb 27. Hypertension. 2012. PMID: 22371359 Free PMC article.

  • Genetic architecture of complex traits predisposing to nephropathy: hypertension.

    Hunt SC. Hunt SC. Semin Nephrol. 2010 Mar;30(2):150-63. doi: 10.1016/j.semnephrol.2010.01.006. Semin Nephrol. 2010. PMID: 20347644 Free PMC article. Review.

  • Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene.

    Pandey VG, Jain S, Rana A, Puri N, Arudra SK, Mopidevi B, Kaw M, Nasjletti A, Kumar A. Pandey VG, et al. J Biol Chem. 2015 Feb 27;290(9):5749-58. doi: 10.1074/jbc.M114.601922. Epub 2015 Jan 7. J Biol Chem. 2015. PMID: 25568318 Free PMC article.