Contribution of umami taste substances in human salivation during meal - PubMed

Affiliations

• PMID: 20224181
• DOI: 10.2152/jmi.56.197

Free article

Review

Contribution of umami taste substances in human salivation during meal

Hisayuki Uneyama et al. J Med Invest. 2009.

Free article

Abstract

The oral gustatory perception during a meal has very important physiological roles such as inducing appetite, smoothing mastication and swallowing, promoting digestion and each nutrient availability. One hundred years ago, L-glutamate was discovered as a new taste substance in Japan. Since then, Japanese taste physiologists have lead the research to establish L-glutamate as the prototype molecule for the fifth basic taste (umami taste), in addition to saltiness, sweetness, bitterness and sourness. Meanwhile, various lines of evidence demonstrated that taste perception is linked to taste stimuli-oral/pharyngeal reflexes. In this review, we focus on the efficacy of L-glutamate for human salivation and discuss the possible application of umami taste simulation to the nutritional management for the elderly due to amelioration of their quality of life (QOL).

Similar articles

• Application of umami taste stimulation to remedy hypogeusia based on reflex salivation.

  Sasano T, Satoh-Kuriwada S, Shoji N, Sekine-Hayakawa Y, Kawai M, Uneyama H. Sasano T, et al. Biol Pharm Bull. 2010;33(11):1791-5. doi: 10.1248/bpb.33.1791. Biol Pharm Bull. 2010. PMID: 21048301

• The influence of oral processing, food perception and social aspects on food consumption: a review.

  Pereira LJ, van der Bilt A. Pereira LJ, et al. J Oral Rehabil. 2016 Aug;43(8):630-48. doi: 10.1111/joor.12395. Epub 2016 Apr 8. J Oral Rehabil. 2016. PMID: 27061099 Review.

• Basic properties of umami and effects on humans.

  Yamaguchi S. Yamaguchi S. Physiol Behav. 1991 May;49(5):833-41. doi: 10.1016/0031-9384(91)90192-q. Physiol Behav. 1991. PMID: 1679557

• NaCl and sugar release, salivation and taste during mastication of salted chewing gum.

  Neyraud E, Prinz J, Dransfield E. Neyraud E, et al. Physiol Behav. 2003 Sep;79(4-5):731-7. doi: 10.1016/s0031-9384(03)00187-2. Physiol Behav. 2003. PMID: 12954416 Clinical Trial.

• Glutamate. Its applications in food and contribution to health.

  Jinap S, Hajeb P. Jinap S, et al. Appetite. 2010 Aug;55(1):1-10. doi: 10.1016/j.appet.2010.05.002. Epub 2010 May 12. Appetite. 2010. PMID: 20470841 Review.

Cited by

• Molecular insights into human taste perception and umami tastants: A review.

  Diepeveen J, Moerdijk-Poortvliet TCW, van der Leij FR. Diepeveen J, et al. J Food Sci. 2022 Apr;87(4):1449-1465. doi: 10.1111/1750-3841.16101. Epub 2022 Mar 17. J Food Sci. 2022. PMID: 35301715 Free PMC article. Review.

• Gastric emptying and duodenal motility upon intake of a liquid meal with monosodium glutamate in healthy subjects.

  Teramoto H, Shimizu T, Yogo H, Nishimiya Y, Hori S, Kosugi T, Nakayama S. Teramoto H, et al. Physiol Rep. 2014 Jan 6;2(1):e00187. doi: 10.1002/phy2.187. eCollection 2014 Jan 1. Physiol Rep. 2014. PMID: 24744869 Free PMC article.

• The interactions between different tastes on initiation of reflex swallow elicited by electrical stimulation in humans.

  Otake M, Kurose M, Uchida Y, Hasegawa M, Yamada Y, Saito I, Yamamura K. Otake M, et al. Odontology. 2016 Sep;104(3):282-90. doi: 10.1007/s10266-015-0226-1. Epub 2015 Dec 24. Odontology. 2016. PMID: 26702624

• Effects of oral stimulation with capsaicin on salivary secretion and neural activities in the autonomic system and the brain.

  Kono Y, Kubota A, Taira M, Katsuyama N, Sugimoto K. Kono Y, et al. J Dent Sci. 2018 Jun;13(2):116-123. doi: 10.1016/j.jds.2017.08.007. Epub 2017 Nov 11. J Dent Sci. 2018. PMID: 30895106 Free PMC article.

• Saliva Production and Enjoyment of Real-Food Flavors in People with and Without Dysphagia and/or Xerostomia.

  Dietsch AM, A Pelletier C, Solomon NP. Dietsch AM, et al. Dysphagia. 2018 Dec;33(6):803-808. doi: 10.1007/s00455-018-9905-8. Epub 2018 May 14. Dysphagia. 2018. PMID: 29761380

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • J-STAGE, Japan Science and Technology Information Aggregator, Electronic