Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease - PubMed

Farnesoid X receptor mediates macrophage-intrinsic responses to suppress colitis-induced colon cancer progression.

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Causal associations between gut microbiota and Cholestatic liver diseases: a Mendelian randomization study.

Yang J, Ma G, Wang K, Yang H, Jiang S, Fan Q, Zhou X, Guo G, Han Y. Yang J, et al. Front Med (Lausanne). 2024 Jan 24;11:1342119. doi: 10.3389/fmed.2024.1342119. eCollection 2024. Front Med (Lausanne). 2024. PMID: 38327703 Free PMC article.

How bile acids and the microbiota interact to shape host immunity.

Lee MH, Nuccio SP, Mohanty I, Hagey LR, Dorrestein PC, Chu H, Raffatellu M. Lee MH, et al. Nat Rev Immunol. 2024 Nov;24(11):798-809. doi: 10.1038/s41577-024-01057-x. Epub 2024 Jul 15. Nat Rev Immunol. 2024. PMID: 39009868 Review.

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.

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Bile salt signaling and bile salt-based therapies in cardiometabolic disease.

Groenen CCJ, Nguyen TA, Paulusma CC, van de Graaf SFJ. Groenen CCJ, et al. Clin Sci (Lond). 2024 Jan 10;138(1):1-21. doi: 10.1042/CS20230934. Clin Sci (Lond). 2024. PMID: 38180064 Free PMC article.