Patent literature on mosquito repellent inventions which contain plant essential oils--a review - PubMed

Affiliations

• PMID: 21328177
• DOI: 10.1055/s-0030-1270723

Review

Patent literature on mosquito repellent inventions which contain plant essential oils--a review

Adrian Martin Pohlit et al. Planta Med. 2011 Apr.

Abstract

Bites Bites of mosquitoes belonging to the genera Anopheles Meigen, Aedes Meigen, Culex L. and Haemagogus L. are a general nuisance and are responsible for the transmission of important tropical diseases such as malaria, hemorrhagic dengue and yellow fevers and filariasis (elephantiasis). Plants are traditional sources of mosquito repelling essential oils (EOs), glyceridic oils and repellent and synergistic chemicals. A Chemical Abstracts search on mosquito repellent inventions containing plant-derived EOs revealed 144 active patents mostly from Asia. Chinese, Japanese and Korean language patents and those of India (in English) accounted for roughly 3/4 of all patents. Since 1998 patents on EO-containing mosquito repellent inventions have almost doubled about every 4 years. In general, these patents describe repellent compositions for use in topical agents, cosmetic products, incense, fumigants, indoor and outdoor sprays, fibers, textiles among other applications. 67 EOs and 9 glyceridic oils were individually cited in at least 2 patents. Over 1/2 of all patents named just one EO. Citronella [Cymbopogon nardus (L.) Rendle, C.winterianus Jowitt ex Bor] and eucalyptus (Eucalyptus LʼHér. spp.) EOs were each cited in approximately 1/3 of all patents. Camphor [Cinnamomum camphora (L.) J. Presl], cinnamon (Cinnamomum zeylanicum Blume), clove [Syzygium aromaticum (L.) Merr. & L.M. Perry], geranium (Pelargonium graveolens LʼHér.), lavender (Lavandula angustifolia Mill.), lemon [Citrus × limon (L.) Osbeck], lemongrass [Cymbopogon citratus (DC.) Stapf] and peppermint (Mentha × piperita L.) EOs were each cited in > 10% of patents. Repellent chemicals present in EO compositions or added as pure “natural” ingredients such as geraniol, limonene, p-menthane-3,8-diol, nepetalactone and vanillin were described in approximately 40% of all patents. About 25% of EO-containing inventions included or were made to be used with synthetic insect control agents having mosquito repellent properties such as pyrethroids, N,N-diethyl-m-toluamide (DEET), (±)-p-menthane-3,8-diol (PMD) and dialkyl phthalates. Synergistic effects involving one or more EOs and synthetic and/or natural components were claimed in about 10% of all patents. Scientific literature sources provide evidence for the mosquito repellency of many of the EOs and individual chemical components found in EOs used in patented repellent inventions.

Similar articles

• Lemongrass and Cinnamon Bark: Plant Essential Oil Blend as a Spatial Repellent for Mosquitoes in a Field Setting.

  Peach DAH, Almond M, Gries R, Gries G. Peach DAH, et al. J Med Entomol. 2019 Sep 3;56(5):1346-1352. doi: 10.1093/jme/tjz078. J Med Entomol. 2019. PMID: 31143941

• Repellent activity of essential oils: a review.

  Nerio LS, Olivero-Verbel J, Stashenko E. Nerio LS, et al. Bioresour Technol. 2010 Jan;101(1):372-8. doi: 10.1016/j.biortech.2009.07.048. Epub 2009 Sep 2. Bioresour Technol. 2010. PMID: 19729299 Review.

• "Singing in the Tube"--audiovisual assay of plant oil repellent activity against mosquitoes (Culex pipiens).

  Adams TF, Wongchai C, Chaidee A, Pfeiffer W. Adams TF, et al. Parasitol Res. 2016 Jan;115(1):225-39. doi: 10.1007/s00436-015-4739-x. Epub 2015 Sep 28. Parasitol Res. 2016. PMID: 26412058

• The fabrication and assessment of mosquito repellent cream for outdoor protection.

  Hazarika H, Krishnatreyya H, Tyagi V, Islam J, Gogoi N, Goyary D, Chattopadhyay P, Zaman K. Hazarika H, et al. Sci Rep. 2022 Feb 9;12(1):2180. doi: 10.1038/s41598-022-06185-9. Sci Rep. 2022. PMID: 35140283 Free PMC article.

• Plant extracts, isolated phytochemicals, and plant-derived agents which are lethal to arthropod vectors of human tropical diseases--a review.

  Pohlit AM, Rezende AR, Lopes Baldin EL, Lopes NP, Neto VF. Pohlit AM, et al. Planta Med. 2011 Apr;77(6):618-30. doi: 10.1055/s-0030-1270949. Epub 2011 Mar 22. Planta Med. 2011. PMID: 21432748 Review.

Cited by

• Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

  Pohlit AM, Lima RB, Frausin G, Silva LF, Lopes SC, Moraes CB, Cravo P, Lacerda MV, Siqueira AM, Freitas-Junior LH, Costa FT. Pohlit AM, et al. Molecules. 2013 Aug 2;18(8):9219-40. doi: 10.3390/molecules18089219. Molecules. 2013. PMID: 23917112 Free PMC article. Review.

• Synthesis of copaiba (Copaifera officinalis) oil nanoemulsion and the potential against Zika virus: An in vitro study.

  Carvalho T, Landim MG, Lima MLD, Bittar C, Faria BCAO, Rahal P, de Lima MCF, Junior VFDV, Joanitti GA, Calmon MF. Carvalho T, et al. PLoS One. 2023 Sep 7;18(9):e0283817. doi: 10.1371/journal.pone.0283817. eCollection 2023. PLoS One. 2023. PMID: 37676868 Free PMC article.

• Pharmacological and phytochemical appraisal of selected medicinal plants from jordan with claimed antidiabetic activities.

  Afifi FU, Kasabri V. Afifi FU, et al. Sci Pharm. 2013 Oct 15;81(4):889-932. doi: 10.3797/scipharm.1212-20. Print 2013 Oct-Dec. Sci Pharm. 2013. PMID: 24482764 Free PMC article. Review.

• A Dietary Plant Extract Formulation Helps Reduce Flea Populations in Cats: A Double-Blind Randomized Study.

  Banuls D, Brun J, Blua JL, Cadiergues MC. Banuls D, et al. Pharmaceuticals (Basel). 2023 Jan 28;16(2):195. doi: 10.3390/ph16020195. Pharmaceuticals (Basel). 2023. PMID: 37259343 Free PMC article.

• Analysis of chemical constituents and antinociceptive potential of essential oil of Teucrium Stocksianum bioss collected from the North West of Pakistan.

  Shah SM, Ullah F, Shah SM, Zahoor M, Sadiq A. Shah SM, et al. BMC Complement Altern Med. 2012 Dec 5;12:244. doi: 10.1186/1472-6882-12-244. BMC Complement Altern Med. 2012. PMID: 23217213 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Georg Thieme Verlag Stuttgart, New York

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal