Anaphylaxis caused by Hymenoptera stings: from epidemiology to treatment - PubMed
Anaphylaxis caused by Hymenoptera stings: from epidemiology to treatment
M B Bilò. Allergy. 2011 Jul.
Abstract
Hymenoptera venom allergy occasionally causes fatal reactions. The prevalence of systemic reactions (SRs) is 0.3-8.9%, with anaphylaxis in 0.3-42.8% of cases. Factors contributing to reaction severity include older age, insect type, a previous less severe SR, preexisting diseases, concomitant treatments, mast cell diseases and elevated baseline tryptase serum concentration. Venom immunotherapy (VIT) is highly effective, as shown by sting challenge and spontaneous field stings. Indications for VIT are based on history of an SR, positive diagnostic tests, natural history and established risk factors for a severe outcome. Current strategies for reducing adverse reactions include anti-IgE monoclonal antibody pretreatment, and purified aqueous and purified aluminium hydroxide adsorbed preparations. New strategies for VIT, mostly using recombinant allergen, are in development. Further improvements will increase the safety and efficacy of VIT.
© 2011 John Wiley & Sons A/S.
Similar articles
-
Przybilla B, Ruëff F. Przybilla B, et al. J Dtsch Dermatol Ges. 2010 Feb;8(2):114-27; quiz 128-30. doi: 10.1111/j.1610-0387.2009.07125.x. Epub 2009 Sep 14. J Dtsch Dermatol Ges. 2010. PMID: 19751222 Review. English, German.
-
Hymenoptera venom immunotherapy and field stings.
Lang R, Hawranek T. Lang R, et al. J Investig Allergol Clin Immunol. 2006;16(4):224-31. J Investig Allergol Clin Immunol. 2006. PMID: 16889279
-
Diagnosis of Hymenoptera venom allergy.
Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JN; EAACI Interest Group on Insect Venom Hypersensitivity. Biló BM, et al. Allergy. 2005 Nov;60(11):1339-49. doi: 10.1111/j.1398-9995.2005.00963.x. Allergy. 2005. PMID: 16197464 Review.
-
[New variants of diagnostic procedures and therapeutic methods in insect venom allergy].
Nittner-Marszalska M. Nittner-Marszalska M. Pol Merkur Lekarski. 2003 Jun;14(84):700-2. Pol Merkur Lekarski. 2003. PMID: 14524309 Review. Polish.
-
Predictors of clinical effectiveness of Hymenoptera venom immunotherapy.
Ruëff F, Vos B, Oude Elberink J, Bender A, Chatelain R, Dugas-Breit S, Horny HP, Küchenhoff H, Linhardt A, Mastnik S, Sotlar K, Stretz E, Vollrath R, Przybilla B, Flaig M. Ruëff F, et al. Clin Exp Allergy. 2014;44(5):736-46. doi: 10.1111/cea.12275. Clin Exp Allergy. 2014. PMID: 24447114
Cited by
-
Scratching the Surface of an Itch: Molecular Evolution of Aculeata Venom Allergens.
Baumann K, Dashevsky D, Sunagar K, Fry B. Baumann K, et al. J Mol Evol. 2018 Aug;86(7):484-500. doi: 10.1007/s00239-018-9860-x. Epub 2018 Jul 31. J Mol Evol. 2018. PMID: 30066019
-
Micaletto S, Ruetzler K, Bruesch M, Schmid-Grendelmeier P. Micaletto S, et al. Allergy Asthma Clin Immunol. 2022 Jun 2;18(1):44. doi: 10.1186/s13223-022-00687-x. Allergy Asthma Clin Immunol. 2022. PMID: 35655287 Free PMC article.
-
Čelesnik Smodiš N, Šilar M, Eržen R, Rijavec M, Košnik M, Korošec P. Čelesnik Smodiš N, et al. PLoS One. 2014 Apr 14;9(4):e94762. doi: 10.1371/journal.pone.0094762. eCollection 2014. PLoS One. 2014. PMID: 24733549 Free PMC article.
-
Bilò MB, Corsi A, Pravettoni V, Bignardi D, Bonadonna P, Quercia O, Mauro M, Novembre E, Micheletti R, Papa R. Bilò MB, et al. Clin Transl Allergy. 2020 Mar 4;10:8. doi: 10.1186/s13601-020-00312-3. eCollection 2020. Clin Transl Allergy. 2020. PMID: 32158533 Free PMC article.
-
Hymenoptera venom allergy: work disability and occupational impact of venom immunotherapy.
Paolocci G, Folletti I, Torén K, Muzi G, Murgia N. Paolocci G, et al. BMJ Open. 2014 Aug 6;4(8):e005593. doi: 10.1136/bmjopen-2014-005593. BMJ Open. 2014. PMID: 25099935 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials