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Liver complications in celiac disease - PubMed

Liver complications in celiac disease

Mohammad Reza Zali et al. Hepat Mon. 2011 May.

Abstract

Celiac disease (CD) is characterized by sensitivity to gluten, which is found in dietary wheat, barley, and rye. Many extra-intestinal manifestations have been described in association with CD. Liver disease and CD share widespread risk factors. Liver disorders such as autoimmune hepatitis, elevation of liver enzyme levels, primary biliary cirrhosis, nonspecific hepatitis, primary sclerosing cholangitis, and nonalcoholic fatty liver disease have been reported in patients with CD. In this review, we provide information regarding liver disorders that may be found in association with celiac disease and the effect of the treatment of CD on these disorders.

Keywords: Celiac disease; Epidemiology; Liver.

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Conflict of interest statement

Conflict of interest: None declared

Figures

Figure 1
Figure 1

Possible pathogenic mechanisms of liver abnormalities in CD

Figure 2
Figure 2

Approach to the diagnosis of liver abnormalities in celiac disease

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References

    1. Rostami Nejad M, Rostami K, Pourhoseingholi MA, Nazemalhosseini Mojarad E, Habibi M, Dabiri H, Zali MR. Atypical presentation is dominant and typical for coeliac disease. J Gastrointestin Liver Dis. 2009;18(3):285–91. - PubMed
    1. Shahbazkhani B, Malekzadeh R, Sotoudeh M, Moghadam KF, Farhadi M, Ansari R, Elahyfar A, Rostami K. High prevalence of coeliac disease in apparently healthy Iranian blood donors. Eur J Gastroenterol Hepatol. 2003;15(5):475–8. - PubMed
    1. Rostami K, Villanacci V. Microscopic enteritis: novel prospect in coeliac disease clinical and immuno-histogenesis. Evolution in diagnostic and treatment strategies. Dig Liver Dis. 2009;41(4):245–52. - PubMed
    1. Abenavoli L, Proietti I, Leggio L, Ferrulli A, Vonghia L, Capizzi R, Rotoli M, Amerio PL, Gasbarrini G, Addolorato G. Cutaneous manifestations in celiac disease. World J Gastroenterol. 2006;12(6):843–52. - PMC - PubMed
    1. Volta U, Ravaglia G, Granito A, Forti P, Maioli F, Petrolini N, Zoli M, Bianchi FB. Coeliac disease in patients with autoimmune thyroiditis. Digestion. 2001;64(1):61–5. - PubMed

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