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Granulomatous reaction to silicone injection - PubMed

Granulomatous reaction to silicone injection

Lixia Z Ellis et al. J Clin Aesthet Dermatol. 2012 Jul.

Abstract

The use of liquid injectable silicone for soft tissue augmentation is controversial. Proponents of its use consider it safe when highly purified medical-grade product is employed appropriately by well-trained and experienced physicians, whereas opponents believe complications from silicone injections are inherently inevitable and unpredictable and that they outweigh the benefits. One of the feared complications is granuloma formation. In this article, the authors report two cases of granulomatous nodules from silicone injections and present the histological features. These cases highlight the need for continued vigilance among clinicians about this complication and the importance not only of careful selection of filler products, but also of patients knowing the credentials of their injection practitioners.

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Conflict of interest statement

DISCLOSURE:The authors report no relevant conflicts of interest.

Figures

Figure 1
Figure 1

The granulomatous nodules of Patient 1 along the bilateral nasolabial folds prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 1 (C: 50x; D: 200x).

Figure 1
Figure 1

The granulomatous nodules of Patient 1 along the bilateral nasolabial folds prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 1 (C: 50x; D: 200x).

Figure 1
Figure 1

The granulomatous nodules of Patient 1 along the bilateral nasolabial folds prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 1 (C: 50x; D: 200x).

Figure 2
Figure 2

The granulomatous nodules of Patient 2 at the upper and lower lips prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 2 (C: 50x with 12.5x as the inset; D: 200x).

Figure 2
Figure 2

The granulomatous nodules of Patient 2 at the upper and lower lips prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 2 (C: 50x with 12.5x as the inset; D: 200x).

Figure 2
Figure 2

The granulomatous nodules of Patient 2 at the upper and lower lips prior to (A) and after treatment (B). Histopathological features of the nodular lesions from Patient 2 (C: 50x with 12.5x as the inset; D: 200x).

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