Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast - PubMed

Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast

D Gozalbo et al. Curr Genet. 1990 Jan.

Abstract

suc2 degrees is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2 degrees had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2 degree strains to ferment sucrose caused an increase of the SUC-specific mRNA level.

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