Review of the enzymatic machinery of Halothermothrix orenii with special reference to industrial applications - PubMed
- ️Wed Jan 01 2014
Review
Review of the enzymatic machinery of Halothermothrix orenii with special reference to industrial applications
Abhishek Bhattacharya et al. Enzyme Microb Technol. 2014.
Abstract
Over the past few decades the extremes at which life thrives has continued to challenge our understanding of physiology, biochemistry, microbial ecology and evolution. Innovative culturing approaches, environmental genome sequencing, and whole genome sequencing have provided new opportunities for the biotechnological exploration of extremophiles. The whole genome sequencing of H. orenii has provided valuable insights not only into the survival and adaptation strategies of thermohalophiles but has also led to the identification of genes encoding biotechnologically relevant enzymes. The present review focuses on the purified and characterized enzymes from H. orenii including amylases, β-glucosidase, fructokinase, and ribokinase--along with uncharacterized but industrially important enzymes encoded by the genes identified in the genome such as β-galactosidases, mannosidases, pullulanases, chitinases, α-L-arabinofuranosidases and other glycosyl hydrolases of commercial interest. This review highlights the importance of the enzymes and their applications in different sectors and why future research for exploring the enzymatic machinery of H. orenii should focus on the expression, purification, and characterization of the novel proteins in H. orenii and their feasible application to pertinent industrial sectors. H. orenii is an anaerobe; genome sequencing studies have also revealed the presence of enzymes for gluconeogenesis and fermentation to ethanol and acetate, making H. orenii an attractive strain for the conversion of starch into bioethanol.
Keywords: Extremophile; Extremozymes; Glycosyl hydrolases; Halothermothrix orenii.
Copyright © 2013 Elsevier Inc. All rights reserved.
Similar articles
-
Marine extremophiles: a source of hydrolases for biotechnological applications.
Dalmaso GZ, Ferreira D, Vermelho AB. Dalmaso GZ, et al. Mar Drugs. 2015 Apr 3;13(4):1925-65. doi: 10.3390/md13041925. Mar Drugs. 2015. PMID: 25854643 Free PMC article. Review.
-
Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii.
Mavromatis K, Ivanova N, Anderson I, Lykidis A, Hooper SD, Sun H, Kunin V, Lapidus A, Hugenholtz P, Patel B, Kyrpides NC. Mavromatis K, et al. PLoS One. 2009;4(1):e4192. doi: 10.1371/journal.pone.0004192. Epub 2009 Jan 15. PLoS One. 2009. PMID: 19145256 Free PMC article.
-
New opportunities revealed by biotechnological explorations of extremophiles.
Podar M, Reysenbach AL. Podar M, et al. Curr Opin Biotechnol. 2006 Jun;17(3):250-5. doi: 10.1016/j.copbio.2006.05.002. Epub 2006 May 15. Curr Opin Biotechnol. 2006. PMID: 16701993 Review.
-
Tan TC, Yien YY, Patel BK, Mijts BN, Swaminathan K. Tan TC, et al. Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2257-8. doi: 10.1107/s0907444903018754. Epub 2003 Nov 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 14646087
-
Tian YS, Xu J, Xiong AS, Zhao W, Gao F, Fu XY, Peng RH, Yao QH. Tian YS, et al. Appl Microbiol Biotechnol. 2012 Jan;93(1):241-50. doi: 10.1007/s00253-011-3443-8. Epub 2011 Jul 1. Appl Microbiol Biotechnol. 2012. PMID: 21720820
Cited by
-
Microbial Diversity in Extreme Marine Habitats and Their Biomolecules.
Poli A, Finore I, Romano I, Gioiello A, Lama L, Nicolaus B. Poli A, et al. Microorganisms. 2017 May 16;5(2):25. doi: 10.3390/microorganisms5020025. Microorganisms. 2017. PMID: 28509857 Free PMC article. Review.
-
Analysis on evolutionary relationship of amylases from archaea, bacteria and eukaryota.
Yan S, Wu G. Yan S, et al. World J Microbiol Biotechnol. 2016 Feb;32(2):24. doi: 10.1007/s11274-015-1979-y. Epub 2016 Jan 8. World J Microbiol Biotechnol. 2016. PMID: 26745984 Free PMC article.
-
Marine extremophiles: a source of hydrolases for biotechnological applications.
Dalmaso GZ, Ferreira D, Vermelho AB. Dalmaso GZ, et al. Mar Drugs. 2015 Apr 3;13(4):1925-65. doi: 10.3390/md13041925. Mar Drugs. 2015. PMID: 25854643 Free PMC article. Review.
-
Marine Microbiological Enzymes: Studies with Multiple Strategies and Prospects.
Wang Y, Song Q, Zhang XH. Wang Y, et al. Mar Drugs. 2016 Sep 22;14(10):171. doi: 10.3390/md14100171. Mar Drugs. 2016. PMID: 27669268 Free PMC article. Review.
-
Release of Soybean Isoflavones by Using a β-Glucosidase from Alicyclobacillus herbarius.
Delgado L, Heckmann CM, Di Pisa F, Gourlay L, Paradisi F. Delgado L, et al. Chembiochem. 2021 Apr 6;22(7):1223-1231. doi: 10.1002/cbic.202000688. Epub 2020 Dec 30. Chembiochem. 2021. PMID: 33237595 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous