pubmed.ncbi.nlm.nih.gov

Post-pericardiotomy syndrome in pediatric patients following surgical closure of secundum atrial septal defects: incidence and risk factors - PubMed

. 2015 Mar;36(3):498-502.

doi: 10.1007/s00246-014-1039-7. Epub 2014 Oct 8.

Affiliations

Post-pericardiotomy syndrome in pediatric patients following surgical closure of secundum atrial septal defects: incidence and risk factors

Howard J Heching et al. Pediatr Cardiol. 2015 Mar.

Abstract

Surgical repair for atrial septal defects (ASD) generally occurs during childhood. Post-pericardiotomy syndrome (PPS) after cardiac surgery has a reported incidence of 1-40 %. We focused exclusively on secundum ASD repair to evaluate the incidence of PPS. The purpose of this study is to determine the incidence of PPS after surgical repair of secundum ASD and investigate what risk factors may be predictive of its development. A retrospective study was performed, and 97 patients who underwent surgical closure of a secundum ASD were identified. 27 (28 %) were diagnosed with PPS within the first postoperative year. Diagnosis was made if they had evidence of new or worsening pericardial effusion and the presence of ≥2 of the following criteria: fever >72 h postoperatively, irritability, pleuritic chest pain, or pericardial friction rub. Closure of secundum ASDs was performed at a median age of 3.8 years (Interquartile Range (IQR): 2.2-6.0 years) and a median weight of 14.3 kilograms (IQR: 10.9-19.3 kilograms). The median time for development of PPS was 8 days post-op (IQR: 5-14). Significantly, 19 (27 %) of 70 patients in the non-PPS group had a small pericardial effusion on their discharge echocardiogram, while of the 27 patients who developed PPS, 17 (63 %) had a small pericardial effusion on their discharge echocardiogram (p = 0.001). PPS is relatively common following surgical closure of secundum ASDs. A small pericardial effusion on discharge echocardiogram is predictive of development of PPS postoperatively. In patients who develop PPS, there is a good response to therapy with a benign course.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Circulation. 1952 Sep;6(3):321-33 - PubMed
    1. Eur Heart J. 2003 Jan;24(2):190-7 - PubMed
    1. Circulation. 1958 Apr;17(4, Part 1):549-56 - PubMed
    1. N Engl J Med. 1990 Dec 13;323(24):1645-50 - PubMed
    1. Eur Heart J. 2010 Nov;31(22):2749-54 - PubMed

MeSH terms

LinkOut - more resources