pubmed.ncbi.nlm.nih.gov

Ongoing challenges for pharmacotherapy for dyslipidemia - PubMed

Review

Ongoing challenges for pharmacotherapy for dyslipidemia

Anthony D Pisaniello et al. Expert Opin Pharmacother. 2015 Feb.

Abstract

Introduction: While increasing evidence has led to lipid-modifying therapy achieving an important role in the treatment guidelines for the prevention of cardiovascular disease, these agents are suboptimally used and there remains a considerable risk of clinical events. Accordingly, there is a need to develop more effective lipid-modifying approaches in many patients.

Areas covered: A literature search was performed of topical manuscripts focusing on factors influencing use of established therapies and new agents in development that target a range of lipid factors.

Expert opinion: More intensive efforts are required to ensure that statin use is maximized in higher risk patients. A range of novel therapies, including proprotein convertase subtilisin kexin-type 9 and cholesteryl ester transfer protein inhibitors, may provide additional protection, although this remains to be established by clinical trials.

Keywords: atherosclerosis; cardiovascular risk; lipid-modifying therapy; lipids.

PubMed Disclaimer

Comment in

  • Current lipid-modifying agents.

    Agouridis AP, Filippatos TD, Katsiki N. Agouridis AP, et al. Expert Opin Pharmacother. 2015 May;16(7):1117-8. doi: 10.1517/14656566.2015.1035013. Epub 2015 Apr 6. Expert Opin Pharmacother. 2015. PMID: 25845932 No abstract available.

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources