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Grape Seed Oil Compounds: Biological and Chemical Actions for Health - PubMed

  • ️Fri Jan 01 2016

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Grape Seed Oil Compounds: Biological and Chemical Actions for Health

Juliano Garavaglia et al. Nutr Metab Insights. 2016.

Abstract

Grape seed oil is rich in phenolic compounds, fatty acids, and vitamins, with economic importance to pharmaceutical, cosmetic, and food industry. Its use as an edible oil has also been suggested, especially due to its pleasant sensory characteristics. Grape seed oil has beneficial properties for health that are mainly detected by in vitro studies, such as anti-inflammatory, cardioprotective, antimicrobial, and anticancer properties, and may interact with cellular and molecular pathways. These effects have been related to grape seed oil constituents, mainly tocopherol, linolenic acid, resveratrol, quercetin, procyanidins, carotenoids, and phytosterols. The aim of this article was to briefly review the composition and nutritional aspects of grape seed oil, the interactions of its compounds with molecular and cellular pathways, and its possible beneficial effects on health.

Keywords: antioxidants; fatty acids; grape seed extract; inflammation.

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References

    1. Bail S, Stuebiger G, Krist S, Unterweger H, Buchbauer G. Characterisation of various grape seed oils by volatile compounds, triacylglycerol composition, total phenols and antioxidant capacity. Food Chem. 2008;108(3):1122–1132. - PubMed
    1. Puiggros F, Llópiz N, Ardévol A, Bladé C, Arola L, Salvadó MJ. Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems. J Agric Food Chem. 2005;53(15):6080–6086. - PubMed
    1. Vinson JA, Mandarano MA, Shuta DL, Bagchi M, Bagchi D. Beneficial effects of a novel IH636 grape seed proanthocyanidin extract and a niacin-bound chromium in a hamster atherosclerosis model. Mol Cell Biochem. 2002;240(1–2):99–103. - PubMed
    1. Wang YJ, Thomas P, Zhong JH, et al. Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer’s disease mouse. Neurotox Res. 2009;15(1):3–14. - PubMed
    1. Brasky TM, Kristal AR, Navarro SL, et al. Specialty supplements and prostate cancer risk in the VITamins and Lifestyle (VITAL) cohort. Nutr Cancer. 2011;63(4):573–582. - PMC - PubMed

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