pubmed.ncbi.nlm.nih.gov

Splenic Infarcts - PubMed

  • ️Mon Jul 17 2023

Book

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.

2023 Jul 17.

Affiliations

Free Books & Documents

Book

Splenic Infarcts

Jennifer Chapman et al.

Free Books & Documents

Excerpt

The spleen is a hematopoietic organ that filters and removes aging blood products and aids in immunity against encapsulated bacterial organisms. Splenic infarction occurs when blood flow to the spleen is compromised, causing tissue ischemia and eventual necrosis. Splenic infarction may be the result of arterial or venous occlusion. Occlusion is usually caused by bland or septic emboli as well as venous congestion by abnormal cells. Infarction may involve a small segmental area of the spleen or may be global, depending on which vessel is occluded. This occurrence is caused by a wide variety of underlying disease states with prognosis dependent on the causative illness. The most typical presentation includes left sided abdominal pain in a patient with underlying hematologic disorder, blood borne malignancy, blunt abdominal trauma, hypercoagulable state, or embolic illness. Treatment of splenic infarction ranges from supportive care to splenectomy.

Therapeutic splenic infarction via splenic embolization has been used to treat hemorrhage from traumatic splenic injuries. Splenic embolization has also been used in the treatment of severe portal hypertension and in the pre-operative phase of splenectomy to reduce intra-operative blood loss.

Copyright © 2025, StatPearls Publishing LLC.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Jennifer Chapman declares no relevant financial relationships with ineligible companies.

Disclosure: Travis Helm declares no relevant financial relationships with ineligible companies.

Disclosure: Chadi Kahwaji declares no relevant financial relationships with ineligible companies.

Similar articles

  • Sickle Cell Disease.

    Bender MA, Carlberg K. Bender MA, et al. 2003 Sep 15 [updated 2025 Feb 13]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2025. 2003 Sep 15 [updated 2025 Feb 13]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2025. PMID: 20301551 Free Books & Documents. Review.

  • Monoclonal Antibody Therapy For High-Risk Coronavirus (COVID 19) Patients With Mild To Moderate Disease Presentations (Archived).

    Aleem A, Vaqar S. Aleem A, et al. 2023 Feb 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Feb 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 34033365 Free Books & Documents.

  • Immediate Hypersensitivity Reactions (Archived).

    Justiz Vaillant AA, Vashisht R, Zito PM. Justiz Vaillant AA, et al. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 May 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30020687 Free Books & Documents.

  • Far Posterior Approach for Rib Fracture Fixation: Surgical Technique and Tips.

    Manes TJ, DeGenova DT, Taylor BC, Patel JN. Manes TJ, et al. JBJS Essent Surg Tech. 2024 Dec 6;14(4):e23.00094. doi: 10.2106/JBJS.ST.23.00094. eCollection 2024 Oct-Dec. JBJS Essent Surg Tech. 2024. PMID: 39650795 Free PMC article.

  • Depressing time: Waiting, melancholia, and the psychoanalytic practice of care.

    Salisbury L, Baraitser L. Salisbury L, et al. In: Kirtsoglou E, Simpson B, editors. The Time of Anthropology: Studies of Contemporary Chronopolitics. Abingdon: Routledge; 2020. Chapter 5. In: Kirtsoglou E, Simpson B, editors. The Time of Anthropology: Studies of Contemporary Chronopolitics. Abingdon: Routledge; 2020. Chapter 5. PMID: 36137063 Free Books & Documents. Review.

References

    1. Kato K, Gleeson TA. Splenic necrosis requiring ultrasound-guided drainage following meningococcal septicaemia. Oxf Med Case Reports. 2019 Mar;2019(3):omz020. - PMC - PubMed
    1. Mamoun C, Houda F. [Splenic infarction revealing infectious endocarditis in a pregnant woman: about a case and brief literature review]. Pan Afr Med J. 2018;30:184. - PMC - PubMed
    1. Niccoli Asabella A, Altini C, Nappi AG, Lavelli V, Ferrari C, Marzullo A, Loiodice A, Rubini G. Sickle cell diseases: What can nuclear medicine offer? Hell J Nucl Med. 2019 Jan-Apr;22(1):2-3. - PubMed
    1. Wand O, Tayer-Shifman OE, Khoury S, Hershko AY. A practical approach to infarction of the spleen as a rare manifestation of multiple common diseases. Ann Med. 2018 Sep;50(6):494-500. - PubMed
    1. Smalls N, Obirieze A, Ehanire I. The impact of coagulopathy on traumatic splenic injuries. Am J Surg. 2015 Oct;210(4):724-9. - PubMed

Publication types