An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome - PubMed

Global discovery of lupus genetic risk variant allelic enhancer activity.

Lu X, Chen X, Forney C, Donmez O, Miller D, Parameswaran S, Hong T, Huang Y, Pujato M, Cazares T, Miraldi ER, Ray JP, de Boer CG, Harley JB, Weirauch MT, Kottyan LC. Lu X, et al. Nat Commun. 2021 Mar 12;12(1):1611. doi: 10.1038/s41467-021-21854-5. Nat Commun. 2021. PMID: 33712590 Free PMC article.

Genome-wide association study identifies 48 common genetic variants associated with handedness.

Cuellar-Partida G, Tung JY, Eriksson N, Albrecht E, Aliev F, Andreassen OA, Barroso I, Beckmann JS, Boks MP, Boomsma DI, Boyd HA, Breteler MMB, Campbell H, Chasman DI, Cherkas LF, Davies G, de Geus EJC, Deary IJ, Deloukas P, Dick DM, Duffy DL, Eriksson JG, Esko T, Feenstra B, Geller F, Gieger C, Giegling I, Gordon SD, Han J, Hansen TF, Hartmann AM, Hayward C, Heikkilä K, Hicks AA, Hirschhorn JN, Hottenga JJ, Huffman JE, Hwang LD, Ikram MA, Kaprio J, Kemp JP, Khaw KT, Klopp N, Konte B, Kutalik Z, Lahti J, Li X, Loos RJF, Luciano M, Magnusson SH, Mangino M, Marques-Vidal P, Martin NG, McArdle WL, McCarthy MI, Medina-Gomez C, Melbye M, Melville SA, Metspalu A, Milani L, Mooser V, Nelis M, Nyholt DR, O'Connell KS, Ophoff RA, Palmer C, Palotie A, Palviainen T, Pare G, Paternoster L, Peltonen L, Penninx BWJH, Polasek O, Pramstaller PP, Prokopenko I, Raikkonen K, Ripatti S, Rivadeneira F, Rudan I, Rujescu D, Smit JH, Smith GD, Smoller JW, Soranzo N, Spector TD, Pourcain BS, Starr JM, Stefánsson H, Steinberg S, Teder-Laving M, Thorleifsson G, Stefánsson K, Timpson NJ, Uitterlinden AG, van Duijn CM, van Rooij FJA, Vink JM, Vollenweider P, Vuoksimaa E, Waeber G, Wareham NJ, Warrington N, Wa… See abstract for full author list ➔ Cuellar-Partida G, et al. Nat Hum Behav. 2021 Jan;5(1):59-70. doi: 10.1038/s41562-020-00956-y. Epub 2020 Sep 28. Nat Hum Behav. 2021. PMID: 32989287 Free PMC article.

Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.

Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Zhang S, et al. Science. 2020 Jul 31;369(6503):561-565. doi: 10.1126/science.aay3983. Science. 2020. PMID: 32732423 Free PMC article.

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases.

Kapoor M, Chao MJ, Johnson EC, Novikova G, Lai D, Meyers JL, Schulman J, Nurnberger JI Jr, Porjesz B, Liu Y; Collaborative Study on the Genetics of Alcoholism (COGA); Foroud T, Edenberg HJ, Marcora E, Agrawal A, Goate A. Kapoor M, et al. Nat Commun. 2021 Aug 20;12(1):5071. doi: 10.1038/s41467-021-25392-y. Nat Commun. 2021. PMID: 34417470 Free PMC article.

Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genes.

Du Z, Lessard S, Iyyanki T, Chao M, Hammond T, Ofengeim D, Klinger K, de Rinaldis E, Shameer K, Chatelain C. Du Z, et al. HGG Adv. 2024 Jul 18;5(3):100317. doi: 10.1016/j.xhgg.2024.100317. Epub 2024 Jun 8. HGG Adv. 2024. PMID: 38851890 Free PMC article.