Prevalence and distribution of cartilage damage at the metacarpal head level in rheumatoid arthritis and osteoarthritis: an ultrasound study - PubMed
- ️Tue Jan 01 2019
Multicenter Study
. 2019 Jul 1;58(7):1206-1213.
doi: 10.1093/rheumatology/key443.
Jana Hurnakova 1 2 3 , Edoardo Cipolletta 1 , Andrea Di Matteo 1 , Fausto Salaffi 1 , Marina Carotti 4 , Antonella Draghessi 1 , Eleonora Di Donato 1 , Marco Di Carlo 1 , Valentina Lato 1 , Rudolf Horvath 3 , Martin Komarc 5 , Karel Pavelka 2 , Walter Grassi 1
Affiliations
- PMID: 30690561
- DOI: 10.1093/rheumatology/key443
Free article
Multicenter Study
Prevalence and distribution of cartilage damage at the metacarpal head level in rheumatoid arthritis and osteoarthritis: an ultrasound study
Jana Hurnakova et al. Rheumatology (Oxford). 2019.
Free article
Abstract
Objectives: To determine the prevalence and distribution of US-detected qualitative cartilage damage at metacarpal heads of patients with RA and hand OA.
Methods: Fifty-two RA patients and 34 patients with hand OA were enrolled. US examination of the metacarpal head cartilage from the II to V finger of both hands was performed. A total of 414 MCP joints in RA and 266 MCP joints in OA patients were scanned with a linear probe up to 22 MHz. Qualitative assessments using a previously described scoring system for cartilage damage were performed. The prevalence and distribution of cartilage damage were analysed. Multivariate regression analysis was used to determine the predictive value of age, gender, BMI, disease duration and the presence of RF and anti-CCP antibodies for US-detected cartilage damage.
Results: The metacarpal head cartilage was positive for cartilage damage in 35.7% (148/414) of MCP joints in RA and in 43.6% (116/266) of MCP joints in OA patients. In RA, the hyaline cartilage of the II and III metacarpal heads (bilaterally) was the most frequently affected. In OA, cartilage damage was more homogeneously distributed in all MCP joints. Multivariate regression analysis showed that age and disease duration, but not gender, BMI or autoantibody status, were independent predictors of US-detected cartilage damage in RA.
Conclusion: Cartilage damage was found in more than one-third of the MCP joints in both RA and OA patients, and in RA patients, the II and III MCP joints were the most damaged.
Keywords: OA; RA; cartilage damage; ultrasonography.
© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Similar articles
-
Filippucci E, da Luz KR, Di Geso L, Salaffi F, Tardella M, Carotti M, Natour J, Grassi W. Filippucci E, et al. Ann Rheum Dis. 2010 Oct;69(10):1845-8. doi: 10.1136/ard.2009.125179. Epub 2010 Jun 22. Ann Rheum Dis. 2010. PMID: 20570837
-
Möller B, Bonel H, Rotzetter M, Villiger PM, Ziswiler HR. Möller B, et al. Arthritis Rheum. 2009 Apr 15;61(4):435-41. doi: 10.1002/art.24424. Arthritis Rheum. 2009. PMID: 19333990
-
Mandl P, Supp G, Baksa G, Radner H, Studenic P, Gyebnar J, Kurucz R, Niedermayer D, Aletaha D, Balint PV, Smolen JS. Mandl P, et al. Ann Rheum Dis. 2015 Nov;74(11):2022-7. doi: 10.1136/annrheumdis-2014-205585. Epub 2014 Jun 24. Ann Rheum Dis. 2015. PMID: 24962872
-
Cartilage damage in osteoarthritis and rheumatoid arthritis--two unequal siblings.
Pap T, Korb-Pap A. Pap T, et al. Nat Rev Rheumatol. 2015 Oct;11(10):606-15. doi: 10.1038/nrrheum.2015.95. Epub 2015 Jul 21. Nat Rev Rheumatol. 2015. PMID: 26195338 Review.
-
Current concepts in the surgical management of rheumatoid and osteoarthritic hands and wrists.
Kozlow JH, Chung KC. Kozlow JH, et al. Hand Clin. 2011 Feb;27(1):31-41. doi: 10.1016/j.hcl.2010.09.003. Epub 2010 Nov 20. Hand Clin. 2011. PMID: 21176798 Free PMC article. Review.
Cited by
-
Cartilage evaluation by ultrasonography in patients with rheumatoid arthritis: a scoping review.
Ogura T, Katagiri T, Kameda H. Ogura T, et al. Inflamm Regen. 2023 Jul 4;43(1):34. doi: 10.1186/s41232-023-00286-2. Inflamm Regen. 2023. PMID: 37403142 Free PMC article.
-
Ultrasound imaging in rheumatoid arthritis.
Filippucci E, Cipolletta E, Mashadi Mirza R, Carotti M, Giovagnoni A, Salaffi F, Tardella M, Di Matteo A, Di Carlo M. Filippucci E, et al. Radiol Med. 2019 Nov;124(11):1087-1100. doi: 10.1007/s11547-019-01002-2. Epub 2019 Mar 9. Radiol Med. 2019. PMID: 30852792 Review.
-
Turning the Page in Osteoarthritis Assessment with the Use of Ultrasound.
Nelson AE. Nelson AE. Curr Rheumatol Rep. 2020 Aug 26;22(10):66. doi: 10.1007/s11926-020-00949-w. Curr Rheumatol Rep. 2020. PMID: 32845396 Free PMC article. Review.
-
Chiu YC, Ho TY, Ting YN, Tsai MT, Huang HL, Hsu CE, Hsu JT. Chiu YC, et al. BMC Musculoskelet Disord. 2021 Feb 5;22(1):146. doi: 10.1186/s12891-020-03939-2. BMC Musculoskelet Disord. 2021. PMID: 33546670 Free PMC article.
-
Vascular supply of the metacarpophalangeal joint.
Baksa G, Czeibert K, Sharp V, Handschuh S, Gyebnar J, Barany L, Benis S, Nyiri G, Mandl P, Petnehazy O, Balint PV. Baksa G, et al. Front Med (Lausanne). 2022 Oct 20;9:1015895. doi: 10.3389/fmed.2022.1015895. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36341235 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous