A Hairy End to a Chilling Event - PubMed

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• PMID: 32763185
• DOI: 10.1016/j.cell.2020.07.004

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A Hairy End to a Chilling Event

Raluca Pascalau et al. Cell. 2020.

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Abstract

In the skin, sympathetic nerves, arrector pili muscles, and hair follicles form a tri-lineage unit to cause piloerection or goosebumps. In this issue of Cell, Schwartz et al. report that, beyond goosebumps, muscle-anchored nerves form "synapse-like" connections with hair follicle stem cells to promote hair regeneration in response to cold.

Comment on

• Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells.

  Shwartz Y, Gonzalez-Celeiro M, Chen CL, Pasolli HA, Sheu SH, Fan SM, Shamsi F, Assaad S, Lin ET, Zhang B, Tsai PC, He M, Tseng YH, Lin SJ, Hsu YC. Shwartz Y, et al. Cell. 2020 Aug 6;182(3):578-593.e19. doi: 10.1016/j.cell.2020.06.031. Epub 2020 Jul 16. Cell. 2020. PMID: 32679029 Free PMC article.

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