Capturing Chromosome Conformation - PubMed

Capturing Chromosome Conformation

Michel Pucéat. Methods Mol Biol. 2021.

Abstract

The genome is organized in 3D topology-associated domains to ensure proper gene transcriptional processes. The chromosome conformation capture (3C) is an affordable method to investigate local chromatin structure and dynamics in cells and tissue. Herein I describe an easy to design and a cost-effective protocol.

Keywords: Chromatin; Chromosome; Topology-associated domain.

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