Sodium restriction can delay the return of hypertension in patients previously well-controlled on drug therapy - PubMed
Clinical Trial
Sodium restriction can delay the return of hypertension in patients previously well-controlled on drug therapy
T Morgan et al. Can J Physiol Pharmacol. 1987 Aug.
Abstract
Sodium restriction can reduce blood pressure in hypertensive patients. The present study indicates that if hypertension is well controlled then the reemergence of hypertension can be decreased by the use of a reduced sodium intake. The present paper demonstrates that in such patients on a normal salt diet, 90% become hypertensive within 6 months while only 40% of people on a reduced sodium diet become hypertensive. It is proposed that a high sodium intake activates a number of amplifiers that causes a shift of the dose-response curve to sodium to the left and if not prevented or interrupted leads to the development of hypertension.
Similar articles
-
Effect of reduction in salt intake on hypertension.
Morgan T, Gillies A. Morgan T, et al. Am Heart J. 1979 Jun;97(6):811-2. doi: 10.1016/0002-8703(79)90019-x. Am Heart J. 1979. PMID: 34991 No abstract available.
-
Sodium in hypertension: clinical aspects and dietary management.
Freis ED. Freis ED. Curr Concepts Nutr. 1981;10:127-30. Curr Concepts Nutr. 1981. PMID: 7249680 No abstract available.
-
Stokes GS, Weber MA, Thornell IR, Stoker LM. Stokes GS, et al. Prog Biochem Pharmacol. 1974;9:29-44. Prog Biochem Pharmacol. 1974. PMID: 4612559 Clinical Trial. No abstract available.
-
Diuretics and alternative drugs in geriatric hypertension.
Moser M. Moser M. Geriatrics. 1987 Feb;42(2):39-44, 49. Geriatrics. 1987. PMID: 3542724 Review.
-
Hypertension in the elderly: treatment.
Schulman SP, Gerstenblith G. Schulman SP, et al. Cardiol Clin. 1986 May;4(2):245-52. Cardiol Clin. 1986. PMID: 2871936 Review.
Cited by
-
Law MR, Frost CD, Wald NJ. Law MR, et al. BMJ. 1991 Apr 6;302(6780):819-24. doi: 10.1136/bmj.302.6780.819. BMJ. 1991. PMID: 1827353 Free PMC article.
-
Graudal NA, Hubeck-Graudal T, Jurgens G. Graudal NA, et al. Cochrane Database Syst Rev. 2017 Apr 9;4(4):CD004022. doi: 10.1002/14651858.CD004022.pub4. Cochrane Database Syst Rev. 2017. PMID: 28391629 Free PMC article. Updated. Review.
-
Reduced dietary salt for the prevention of cardiovascular disease.
Taylor RS, Ashton KE, Moxham T, Hooper L, Ebrahim S. Taylor RS, et al. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD009217. doi: 10.1002/14651858.CD009217. Cochrane Database Syst Rev. 2011. PMID: 21735439 Free PMC article. Updated. Review.
-
Systematic review of long term effects of advice to reduce dietary salt in adults.
Hooper L, Bartlett C, Davey Smith G, Ebrahim S. Hooper L, et al. BMJ. 2002 Sep 21;325(7365):628. doi: 10.1136/bmj.325.7365.628. BMJ. 2002. PMID: 12242173 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical