Neonatal Infant Pain Scale in assessing pain and pain relief for newborn male circumcision - PubMed

Affiliations

• PMID: 35352017
• DOI: 10.1038/s41443-022-00551-x

Review

Neonatal Infant Pain Scale in assessing pain and pain relief for newborn male circumcision

Carlo V Bellieni. Int J Impot Res. 2023 May.

Abstract

Circumcision-partial or total removal of the penile prepuce-requires cutting nerve-laden, sensitive genital tissue and is therefore liable to be painful. The aim of this review is to evaluate the evidence concerning pain felt by newborns during circumcision and to determine whether current analgesic methods can eliminate such pain. I performed a search in medical databases, selecting the trials published in the last 20 years that assessed pain in neonatal circumcision. Twenty-three trials have been retrieved. To get reliable findings, those trials that used validated pain scales were selected; then it was investigated which trials had comparable data for using the same pain scale. The only pain scale that was used in more than two trials was the modified Neonatal Infant Pain Scale (mNIPS) that ranges 0-6. The results of these trials show that none of the analgesic strategies used obtained the absence of pain. Some differences between circumcision techniques can be noticed, but most assessments exceed the score of 3, chosen as the clinically significant pain.

Similar articles

• A video study of pain relief during newborn male circumcision.

  Garry DJ, Swoboda E, Elimian A, Figueroa R. Garry DJ, et al. J Perinatol. 2006 Feb;26(2):106-10. doi: 10.1038/sj.jp.7211413. J Perinatol. 2006. PMID: 16292334 Clinical Trial.

• Effect of lidocaine-prilocaine eutectic mixture of local anaesthetic cream compared with oral sucrose or both in alleviating pain in neonatal circumcision procedure.

  Al Qahtani R, Abu-Salem LY, Pal K. Al Qahtani R, et al. Afr J Paediatr Surg. 2014 Jan-Mar;11(1):56-61. doi: 10.4103/0189-6725.129236. Afr J Paediatr Surg. 2014. PMID: 24647296 Clinical Trial.

• Comparison of ring block, dorsal penile nerve block, and topical anesthesia for neonatal circumcision: a randomized controlled trial.

  Lander J, Brady-Fryer B, Metcalfe JB, Nazarali S, Muttitt S. Lander J, et al. JAMA. 1997 Dec 24-31;278(24):2157-62. JAMA. 1997. PMID: 9417009 Clinical Trial.

• Caudal epidural block versus other methods of postoperative pain relief for circumcision in boys.

  Allan CY, Jacqueline PA, Shubhda JH. Allan CY, et al. Cochrane Database Syst Rev. 2003;(2):CD003005. doi: 10.1002/14651858.CD003005. Cochrane Database Syst Rev. 2003. PMID: 12804449 Updated. Review.

• Pain in neonatal circumcision.

  Schoen EJ, Fischell AA. Schoen EJ, et al. Clin Pediatr (Phila). 1991 Jul;30(7):429-32. doi: 10.1177/000992289103000704. Clin Pediatr (Phila). 1991. PMID: 1879099 Review.

Cited by

• Potentially under-recognized late-stage physical and psychosexual complications of non-therapeutic neonatal penile circumcision: a qualitative and quantitative analysis of self-reports from an online community forum.

  Uberoi M, Abdulcadir J, Ohl DA, Santiago JE, Rana GK, Anderson FWJ. Uberoi M, et al. Int J Impot Res. 2023 May;35(3):234-241. doi: 10.1038/s41443-022-00619-8. Epub 2022 Oct 23. Int J Impot Res. 2023. PMID: 36274189 Review.

References

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Nature Publishing Group

• Medical

  • MedlinePlus Health Information