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Cassia alata, Coriandrum sativum, Curcuma longa and Azadirachta indica: Food Ingredients as Complementary and Alternative Therapies for Atopic Dermatitis-A Comprehensive Review - PubMed

  • ️Sat Jan 01 2022

Review

Cassia alata, Coriandrum sativum, Curcuma longa and Azadirachta indica: Food Ingredients as Complementary and Alternative Therapies for Atopic Dermatitis-A Comprehensive Review

Yik-Ling Chew et al. Molecules. 2022.

Abstract

Traditional medicine is critical in disease treatment and management. Herbs are gaining popularity for disease management and treatment. Therefore, they can be utilised as complementary and alternative treatment (CAT) ingredients. Atopic dermatitis (AD) is one of the common non-communicable diseases. It is characterised by chronic inflammatory skin disease with intense pruritus and eczematous lesions. AD is associated with oxidative stress, microbial infection, and upregulation of inflammatory cytokines. Both children and adults could be affected by this skin disorder. The prevalence of AD is increasing along with the country's level of development. This review revisited the literature on four medicinal herbs widely used as complementary medicine to manage AD. These therapeutic herbs are commonly eaten as food and used as spices in Asian cuisine. The four food herbs reviewed are Cassia alata, Coriandrum sativum, Curcuma longa Linn, and Azadirachta indica. Their traditional uses and phytochemical content will be covered. Four relevant pharmacological and biological activities of the plants crucial in AD management have been reviewed and discussed, including anti-inflammatory, anti-microbial, antioxidant, and wound recovery.

Keywords: complementary and alternative medicine; disease management; eczema; herbal research; integrative medicine; traditional medicine.

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Conflict of interest statement

The authors declare that they have no conflict of interests.

Figures

Figure 1
Figure 1

Cassia alata plant.

Figure 2
Figure 2

Coriandrum sativum plant and seeds.

Figure 3
Figure 3

Curcuma longa rhizomes.

Figure 4
Figure 4

Azadirachta indica plant.

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Grants and funding

The authors would like to acknowledge the support of the Fundamental Research Grant Scheme (FRGS) (FRGS/1/2021/STG02/UCSI/02/1) and UCSI University Pioneer Scientist Incentive Fund (PSIF) research grant (Grant no.: Proj-2019-In-FPS-020).