pubmed.ncbi.nlm.nih.gov

Exopolysaccharides Producing Bacteria: A Review - PubMed

  • ️Sun Jan 01 2023

Review

Exopolysaccharides Producing Bacteria: A Review

Alexander I Netrusov et al. Microorganisms. 2023.

Abstract

Bacterial exopolysaccharides (EPS) are essential natural biopolymers used in different areas including biomedicine, food, cosmetic, petroleum, and pharmaceuticals and also in environmental remediation. The interest in them is primarily due to their unique structure and properties such as biocompatibility, biodegradability, higher purity, hydrophilic nature, anti-inflammatory, antioxidant, anti-cancer, antibacterial, and immune-modulating and prebiotic activities. The present review summarizes the current research progress on bacterial EPSs including their properties, biological functions, and promising applications in the various fields of science, industry, medicine, and technology, as well as characteristics and the isolation sources of EPSs-producing bacterial strains. This review provides an overview of the latest advances in the study of such important industrial exopolysaccharides as xanthan, bacterial cellulose, and levan. Finally, current study limitations and future directions are discussed.

Keywords: bacterial cellulose; bacterial exopolysaccharides; bacterial strains; environmental remediation; levan; xanthan.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1

Bacterial EPS properties, biological activity, application, and sources.

Figure 2
Figure 2

K. sucrofermentans B-11267 isolated from the kombucha community (A). The colony morphology (B). Cell morphology (scale bar: 5 μm) (C). Gel film obtained in static conditions (D). Gel film after purification (E). AFM (atomic force microscopy) image of BC (F). BC agglomerates of various shapes formed in agitated culture conditions (G,H). BC aerogel (I).

Figure 3
Figure 3

Paenibacillus polymyxa 2020, first isolated from wasp honeycombs (A). The colony morphology (B). Cell morphology (C). Chromosome map (D). SEM image of EPS (E). Adapted with permission from Ref. [66].

Figure 4
Figure 4

X.campestris M 28 isolated from cabbage (A). The colony morphology (B). Xanthan production (C).

Similar articles

Cited by

References

    1. Ahuja V., Bhatt A.K., Banu J.R., Kumar V., Kumar G., Yang Y.H., Bhatia S.K. Microbial Exopolysaccharide Composites in Biomedicine and Healthcare: Trends and Advances. Polymers. 2023;15:1801. doi: 10.3390/polym15071801. - DOI - PMC - PubMed
    1. Kaur N., Dey P. Bacterial Exopolysaccharides as Emerging Bioactive Macromolecules: From Fundamentals to Applications. Res. Microbiol. 2022;29:104024. doi: 10.1016/j.resmic.2022.104024. - DOI - PubMed
    1. Mahmoud Y.A.-G., El-Naggar M.E., Abdel-Megeed A., El-Newehy M. Recent Advancements in Microbial Polysaccharides: Synthesis and Applications. Polymers. 2021;13:4136. doi: 10.3390/polym13234136. - DOI - PMC - PubMed
    1. Mohd Nadzir M., Nurhayati R.W., Idris F.N., Nguyen M.H. Biomedical Applications of Bacterial Exopolysaccharides: A Review. Polymers. 2021;13:530. doi: 10.3390/polym13040530. - DOI - PMC - PubMed
    1. Rana S., Upadhyay L.S.B. Microbial exopolysaccharides: Synthesis pathways, types and their commercial applications. Int. J. Biol. Macromol. 2020;157:577–583. doi: 10.1016/j.ijbiomac.2020.04.084. - DOI - PubMed

Publication types

Grants and funding

This work was supported by the Ministry of Science and Higher Education of the Russian Federation within the framework of the academic leadership program «Priority 2030» (grant number 25-22).

LinkOut - more resources