24-h Urinary Calcium Excretion and Renal Outcomes in Hospitalized Patients with and without Chronic Kidney Disease - PubMed

Figure 3

Association between 24-h urinary calcium excretion and risk of renal function decline in 3815 CKD and 1133 non-CKD patients. Data were fit by time-dependent Cox proportional hazards regression models based on restricted cubic splines with four knots and were adjusted for variates. The red dotted lines show 95% confidence intervals. The blue bar charts show the frequency of calcium excretion. Model A was adjusted by age, sex, BMI, MAP, current smoking habit, baseline eGFR, 24-h urine protein, serum calcium, hemoglobin, serum albumin, serum phosphorus, alkaline phosphatase, total cholesterol, triglyceride, urinary sodium excretion, urine potential of hydrogen, CKD etiology, diabetes mellitus, cardiovascular disease, angiotensin-converting enzyme inhibitor (ACE)/angiotensin receptor blocker (ARB) use, glucocorticoids, diuretics, statins, CaCO3 supplements, phosphorus binders, calcitriol, and vitamin D supplements. Model B was adjusted by age, sex, BMI, MAP, eGFR, 24-h urine protein, serum calcium, diabetes, and diuretics use. Abbreviations: CKD, chronic kidney disease; HR (95% CI), hazard ratio (95% confidence interval); UCaE, urinary calcium excretion.