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Fantastic voyage: Chasing oxytocin from the bedside to the bench and back again - PubMed

  • ️Sun Jan 01 2023

Review

Fantastic voyage: Chasing oxytocin from the bedside to the bench and back again

Martha G Welch. Compr Psychoneuroendocrinol. 2023.

Abstract

This is the story of my 50-year career in medicine and research, and the people who influenced and helped me most along the way. I recount the way in which I became interested in oxytocin early in my career as a child psychiatrist, and how it led me back to Columbia University, my alma mater, to study oxytocin's role in mother-child innate behaviors. I recount how oxytocin/oxytocin receptor signaling was central to my basic and clinical research and present a new theory on mother-infant emotional behaviors that challenges 400 years of brain-centric science. My history underscores the important and unique perspective women bring to science and why women are especially needed in the sciences. I hope to inspire young women (and young men) who are beginning their careers in research.

Keywords: Autonomic socioemotional reflex; Innate behavior; Mother/infant behavior; Signaling pathway.

© 2023 Published by Elsevier Ltd.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1

Oxytocin receptor expressed in the epithelium (gut mucosa) of the post-natal day 7 baby rat gut.

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