Glycolipid synthesis in normal and virus-transformed hamster cell lines - PubMed
Glycolipid synthesis in normal and virus-transformed hamster cell lines
H Sakiyama et al. Proc Natl Acad Sci U S A. 1972 Apr.
Abstract
Studies have been continued on the synthesis of glycolipids by the NIL 2 line of hamster cells. Several clones were isolated from this line. These clones vary in morphology, saturation density, and glycolipid composition. Contrary to expectation there was no correlation between saturation density and complexity of the glycolipid pattern. In fact, the clone with the highest saturation density was the only one to show the complete set of glycolipids found previously in NIL 2 cells. All untransformed NIL clones show an increase in the level of "higher" (more than two saccharides/ceramide) glycolipids as the cells approach confluence. In the line containing all three "higher" neutral glycolipids, all three increased as cells approached saturation density. In the line containing only hematoside, this compound increased at confluence. Cells transformed by hamster sarcoma virus or polyoma virus showed no density-dependent glycolipid synthesis.
Similar articles
-
Cell surface modifications in virus-transformed cells--glycolipid changes in the NIL2 hamster cells.
MacPherson I, Critchley DR, Chandrabose KA, Humphrey D. MacPherson I, et al. Johns Hopkins Med J Suppl. 1973;2:46-58. Johns Hopkins Med J Suppl. 1973. PMID: 4369834 No abstract available.
-
Hirschberg CB, Wolf BA, Robbins PW. Hirschberg CB, et al. J Cell Physiol. 1975 Feb;85(1):31-9. doi: 10.1002/jcp.1040850105. J Cell Physiol. 1975. PMID: 1167367
-
Hammarström S, Bjursell G. Hammarström S, et al. FEBS Lett. 1973 May 15;32(1):69-72. doi: 10.1016/0014-5793(73)80739-2. FEBS Lett. 1973. PMID: 4351855 No abstract available.
-
Membrane components and enzymes in virally transformed cells.
Brady RO, Fishman PH, Mora PT. Brady RO, et al. Fed Proc. 1973 Jan;32(1):102-8. Fed Proc. 1973. PMID: 4346325 Review. No abstract available.
-
Composition of membranes of cells transformed by tumorigenic DNA and RNA viruses.
Brady RO. Brady RO. Am J Clin Pathol. 1975 May;63(5):685-94. doi: 10.1093/ajcp/63.5.685. Am J Clin Pathol. 1975. PMID: 165709 Review.
Cited by
-
A consideration of the role of cell surface macromolecules in the process of viral transformation.
Sheinin R, Shopsis C. Sheinin R, et al. In Vitro. 1976 Mar;12(3):198-207. doi: 10.1007/BF02796442. In Vitro. 1976. PMID: 177354
-
Kalckar HM, Ullrey D, Kijomoto S, Hakomori S. Kalckar HM, et al. Proc Natl Acad Sci U S A. 1973 Mar;70(3):839-43. doi: 10.1073/pnas.70.3.839. Proc Natl Acad Sci U S A. 1973. PMID: 4351806 Free PMC article.
-
Neutral glycosphingolipids and gangliosides of human lung and lung tumours.
Narasimhan R, Murray RK. Narasimhan R, et al. Biochem J. 1979 Apr 1;179(1):199-211. doi: 10.1042/bj1790199. Biochem J. 1979. PMID: 475754 Free PMC article.
-
Hakomori S, Wang SM, Young WW Jr. Hakomori S, et al. Proc Natl Acad Sci U S A. 1977 Jul;74(7):3023-7. doi: 10.1073/pnas.74.7.3023. Proc Natl Acad Sci U S A. 1977. PMID: 268649 Free PMC article.
-
The fluidity of normal and virus-transformed cell plasma membrane.
Micklem KJ, Abra RM, Knutton S, Graham JM, Pasternak CA. Micklem KJ, et al. Biochem J. 1976 Mar 15;154(3):561-6. doi: 10.1042/bj1540561a. Biochem J. 1976. PMID: 182120 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials