Serological crossreactivity between H-Y (male) antigens of mouse and man - PubMed

Serological crossreactivity between H-Y (male) antigens of mouse and man

S S Wachtel et al. Proc Natl Acad Sci U S A. 1974 Apr.

Abstract

Antisera to H-Y (male-specific) antigen were prepared by immunizing female mice with spleen cells from males of the same inbred strain. These antisera were used in mixed hemadsorption and cytotoxicity tests with cells of rats, guinea pigs, rabbits, and humans. The results showed that the H-Y components of all four species are antigenically related to H-Y of the mouse.

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