pubmed.ncbi.nlm.nih.gov

Rapid presumptive diagnosis of gonococcal urethritis in men by the limulus lysate test - PubMed

Rapid presumptive diagnosis of gonococcal urethritis in men by the limulus lysate test

V A Spagna et al. Br J Vener Dis. 1979 Jun.

Abstract

In an evaluation of the limulus assay as a method for detecting endotoxin in urethral exudates, positive results of urethral samples at a 1/200 dilution were obtained from 73 out of 73 patients with culture-positive gonococcal urethritis while negative results were obtained from 26 out of 27 patients with cuture-negative urethral specimens. A specimen from one patient, which gave negative results on Gram stain and culture, gave positive results to the limulus test. The overall accuracy of the limulus test for predicting culture results was 99% (p less than 0.001). Thus, in preliminary studies of otherwise healthy men, the results of the limulus assay correlated with those of biological methods for diagnosing urethral gonorrhoea; the test may, therefore, be of use in identifying cases of nongonococcal urethritis.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Br Med J. 1960 Jul 9;2(5192):113-5 - PubMed
    1. Bull Johns Hopkins Hosp. 1964 Sep;115:265-74 - PubMed
    1. Ann Intern Med. 1975 Jan;82(1):7-12 - PubMed
    1. J Clin Invest. 1977 Nov;60(5):1149-58 - PubMed
    1. JAMA. 1977 Feb 28;237(9):896-7 - PubMed

MeSH terms

LinkOut - more resources