A flexible procedure for multiple cadaveric organ procurement - PubMed
. 1984 Mar;158(3):223-30.
- PMID: 6367113
- PMCID: PMC2728063
A flexible procedure for multiple cadaveric organ procurement
T E Starzl et al. Surg Gynecol Obstet. 1984 Mar.
Abstract
Techniques have been developed which permit removal of the kidneys, liver, heart and other organs from the same donor without jeopardy to any of the individual grafts. The guiding principle is avoidance with all organs of warm ischemia. This is achieved by carefully timed and controlled infusion of cold solutions into anatomic regions, the limits of which are defined by preliminary dissection.
Figures

Total midline incision used for multiple organ procurement.

Nephrectomy: preliminary steps for in situ infusion of kidneys in a cadaveric donor with an effective circulation who has been pronounced dead as a result of neurologic criteria.

A and B, Nephrectomy. preparation for in situ infusion by encircling the aorta just above or alternatively just below the diaphragm

Nephrectomy: in situ infusion of kidneys with cold preservation fluid through the distal part of the aorta, with a venous bleed-off from the distal inferior vena cava. The aorta is clamped proximally at one of the sites shown in Figure 3.

A and B, Nephrectomy: removal of perfused kidneys en bloc. The kidneys and great vessels are held anterior to the plane of scissors dissection.

A, Placement of kidneys in an ice basin. B, Division of kidneys using a posterior approach to split the aorta.

Removal of segments of iliac arteries and veins and thoracic aorta. The vascular grafts are refrigerated and kept in case of an emergency.

Hepatectomy hilar dissection and transection of the common bile duct as an initial step in multiple organ harvesting. Note that the splenic vein (or alternatively the superior mesenteric vein) is cannulated for eventual delivery of preservation fluid.

In situ infusion technique used when the kidneys and liver are removed from the same donor. R.g.a., Right gastric artery; G.d.a., gastroduodenal artery; S.a., splenic artery; S.v., splenic vein; P.v., portal vein, and S.m.v., Superior mesenteric vein.

Final steps if the heart is to be removed in combination with nephrectomies or hepatectomy, or both. See text for details.
Similar articles
-
Taylor RJ, Rosenthal JT, Hakala TR. Taylor RJ, et al. Arch Surg. 1985 Sep;120(9):1084-5. doi: 10.1001/archsurg.1985.01390330090020. Arch Surg. 1985. PMID: 3896200
-
Multiple cadaveric organ procurement for transplantation with emphasis on the heart.
Hardesty RL, Griffith BP. Hardesty RL, et al. Surg Clin North Am. 1986 Jun;66(3):451-7. doi: 10.1016/s0039-6109(16)43932-0. Surg Clin North Am. 1986. PMID: 3520888
-
An improved technique for multiple organ harvesting.
Starzl TE, Miller C, Broznick B, Makowka L. Starzl TE, et al. Surg Gynecol Obstet. 1987 Oct;165(4):343-8. Surg Gynecol Obstet. 1987. PMID: 3310285 Free PMC article.
-
Procurement and preservation of cadaver kidneys.
Barry JM. Barry JM. Urol Clin North Am. 1983 May;10(2):205-16. Urol Clin North Am. 1983. PMID: 6344384 Review. No abstract available.
-
Procurement, preservation, and transport of cadaver kidneys.
Van der Werf WJ, D'Alessandro AM, Hoffmann RM, Knechtle SJ. Van der Werf WJ, et al. Surg Clin North Am. 1998 Feb;78(1):41-54. doi: 10.1016/s0039-6109(05)70633-2. Surg Clin North Am. 1998. PMID: 9531934 Review.
Cited by
-
Rapid donor liver procurement with only aortic perfusion.
Lin QY, Chui KK, Rao AN. Lin QY, et al. World J Gastroenterol. 2001 Dec;7(6):884-6. doi: 10.3748/wjg.v7.i6.884. World J Gastroenterol. 2001. PMID: 11854923 Free PMC article.
-
Renal Procurement: Techniques for Optimizing the Quality of the Graft in the Cadaveric Setting.
Tavares-da-Silva E, Figueiredo A. Tavares-da-Silva E, et al. Curr Urol Rep. 2020 Mar 13;21(2):12. doi: 10.1007/s11934-020-0963-8. Curr Urol Rep. 2020. PMID: 32166407 Review.
-
González J, Gaynor JJ, Alameddine M, Ciancio G. González J, et al. Curr Urol Rep. 2018 Feb 5;19(3):6. doi: 10.1007/s11934-018-0753-8. Curr Urol Rep. 2018. PMID: 29399723 Review.
-
Huang C, Huang S, Tang Y, Zhao Q, Wang D, Ju W, Yang L, Zhang J, Wu L, Chen M, Zhang Z, Zhu Z, Wang L, Zhu C, Zhang Y, Sun C, Xiong W, Shen Y, Chen X, Ma Y, Hu A, Zhu X, Rong J, Cai C, Guo Z, He X. Huang C, et al. BMJ Open. 2020 May 5;10(5):e035374. doi: 10.1136/bmjopen-2019-035374. BMJ Open. 2020. PMID: 32376754 Free PMC article.
-
Experience with liver and kidney allografts from non-heart-beating donors.
Casavilla A, Ramirez C, Shapiro R, Nghiem D, Miracle K, Bronsther O, Randhawa P, Broznick B, Fung JJ, Starzl T. Casavilla A, et al. Transplantation. 1995 Jan 27;59(2):197-203. doi: 10.1097/00007890-199501000-00008. Transplantation. 1995. PMID: 7839441 Free PMC article.
References
-
- Starzl TE. Experience in Renal Transplantation. Philadelphia: W. B. Saunders Co.; 1964. pp. 68–71.
-
- Collins GM, Bravo-Shugarman M, Terasaki PI. Kidney preservation for transportation. Lancet. 1969;2:1219–1222. - PubMed
-
- Ackerman JR, Snell ME. Cadaveric renal transplantation. Br. J .Urol. 1968;40:515–521. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical