Staphylococcin 1580 is identical to the lantibiotic epidermin: implications for the nature of bacteriocins from gram-positive bacteria - PubMed

Staphylococcin 1580 is identical to the lantibiotic epidermin: implications for the nature of bacteriocins from gram-positive bacteria

H G Sahl. Appl Environ Microbiol. 1994 Feb.

Abstract

Staphylococcin 1580 was purified to homogeneity from culture supernatants of Staphylococcus epidermidis 1580 by means of adsorption to XAD 2, cation exchange chromatography, and high-performance liquid chromatography on reversed-phase C18. The purified active substance migrated in sodium dodecyl sulfate-polyacrylamide gel electrophoresis with an apparent M(r) of approximately 2,000. Amino acid analysis, mass determination (2,165 Da) and N-terminal sequencing (Ile-Ala-Xaa-Lys-Phe-Ile-Xaa-Xaa-Pro-Gly-Xaa-Ala-Lys-block) demonstrated that staphylococcin 1580 is identical to epidermin, a lanthionine-containing antibiotic peptide (lantibiotic).

Similar articles

• Identification, characterization and purification of the lantibiotic staphylococcin T, a natural gallidermin variant.

  Furmanek B, Kaczorowski T, Bugalski R, Bielawski K, Bohdanowicz J, Podhajska AJ. Furmanek B, et al. J Appl Microbiol. 1999 Dec;87(6):856-66. doi: 10.1046/j.1365-2672.1999.00937.x. J Appl Microbiol. 1999. PMID: 10664909

• Isolation of a new epidermin variant from two strains of Staphylococcus epidermidis--frequency of lantibiotic production in coagulase-negative staphylococci.

  Israil AM, Jack RW, Jung G, Sahl HG. Israil AM, et al. Zentralbl Bakteriol. 1996 Jul;284(2-3):285-96. doi: 10.1016/s0934-8840(96)80104-6. Zentralbl Bakteriol. 1996. PMID: 8837389

• Lantibiotic-mediated anti-lactobacillus activity of a vaginal Staphylococcus aureus isolate.

  Scott JC, Sahl HG, Carne A, Tagg JR. Scott JC, et al. FEMS Microbiol Lett. 1992 May 15;72(1):97-102. doi: 10.1016/0378-1097(92)90496-b. FEMS Microbiol Lett. 1992. PMID: 1612423

• Structure and genetics of circular bacteriocins.

  van Belkum MJ, Martin-Visscher LA, Vederas JC. van Belkum MJ, et al. Trends Microbiol. 2011 Aug;19(8):411-8. doi: 10.1016/j.tim.2011.04.004. Epub 2011 Jun 12. Trends Microbiol. 2011. PMID: 21664137 Review.

• Structure-function relationships of the non-lanthionine-containing peptide (class II) bacteriocins produced by gram-positive bacteria.

  Nissen-Meyer J, Rogne P, Oppegård C, Haugen HS, Kristiansen PE. Nissen-Meyer J, et al. Curr Pharm Biotechnol. 2009 Jan;10(1):19-37. doi: 10.2174/138920109787048661. Curr Pharm Biotechnol. 2009. PMID: 19149588 Review.

Cited by

• A plant endophyte Staphylococcus hominis strain MBL_AB63 produces a novel lantibiotic, homicorcin and a position one variant.

  Aftab Uddin M, Akter S, Ferdous M, Haidar B, Amin A, Shofiul Islam Molla AHM, Khan H, Islam MR. Aftab Uddin M, et al. Sci Rep. 2021 May 27;11(1):11211. doi: 10.1038/s41598-021-90613-9. Sci Rep. 2021. PMID: 34045548 Free PMC article.

• Bacteriocins of gram-positive bacteria.

  Jack RW, Tagg JR, Ray B. Jack RW, et al. Microbiol Rev. 1995 Jun;59(2):171-200. doi: 10.1128/mr.59.2.171-200.1995. Microbiol Rev. 1995. PMID: 7603408 Free PMC article. Review.

• Two-component anti-Staphylococcus aureus lantibiotic activity produced by Staphylococcus aureus C55.

  Navaratna MA, Sahl HG, Tagg JR. Navaratna MA, et al. Appl Environ Microbiol. 1998 Dec;64(12):4803-8. doi: 10.1128/AEM.64.12.4803-4808.1998. Appl Environ Microbiol. 1998. PMID: 9835565 Free PMC article.

• Enhanced production, purification, characterization and mechanism of action of salivaricin 9 lantibiotic produced by Streptococcus salivarius NU10.

  Barbour A, Philip K, Muniandy S. Barbour A, et al. PLoS One. 2013 Oct 16;8(10):e77751. doi: 10.1371/journal.pone.0077751. eCollection 2013. PLoS One. 2013. PMID: 24147072 Free PMC article.

• The biosynthesis of the lantibiotics epidermin, gallidermin, Pep5 and epilancin K7.

  Bierbaum G, Götz F, Peschel A, Kupke T, van de Kamp M, Sahl HG. Bierbaum G, et al. Antonie Van Leeuwenhoek. 1996 Feb;69(2):119-127. doi: 10.1007/BF00399417. Antonie Van Leeuwenhoek. 1996. PMID: 8775972 Review.

References

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Atypon
  • Europe PubMed Central
  • PubMed Central

• Medical

  • MedlinePlus Health Information