Adverse consequences of lysergic acid diethylamide - PubMed
Review
Adverse consequences of lysergic acid diethylamide
H D Abraham et al. Addiction. 1993 Oct.
Abstract
The continued endemic use of hallucinogenic drugs, and of LSD in particular, raises concern regarding their short and long term adverse consequences. The epidemiology of LSD abuse is reviewed suggesting an increase in LSD use among the young as the prevalence rates for other substances continues to fall. Evidence supports the association of LSD use with panic reactions, prolonged schizoaffective psychoses and post-hallucinogen perceptual disorder, the latter being present continually for as long as 5 years. Evidence does not support claims of genetic disorders arising from hallucinogens. In light of the foregoing, current data confirm earlier findings of long lasting psychopathology arising in vulnerable individuals from the use of LSD. A hypothetical long term molecular mechanism of adverse effects is proposed.
Comment in
-
LSD and post-hallucinogen perceptual disorder.
Madden JS. Madden JS. Addiction. 1994 Jun;89(6):762-3. doi: 10.1111/j.1360-0443.1994.tb00966.x. Addiction. 1994. PMID: 7993428 No abstract available.
Similar articles
-
[Hallucinogen-induced psychological disorders].
Hermle L, Kovar KA, Hewer W, Ruchsow M. Hermle L, et al. Fortschr Neurol Psychiatr. 2008 Jun;76(6):334-42. doi: 10.1055/s-2008-1038191. Fortschr Neurol Psychiatr. 2008. PMID: 18512184 Review. German.
-
[Hallucinogen caused motility disorders in rats as potential psychosis relevant animal model].
Oelssner W. Oelssner W. Samml Zwangl Abh Geb Psychiatr Neurol. 1982;50:53-60. Samml Zwangl Abh Geb Psychiatr Neurol. 1982. PMID: 7157125 German. No abstract available.
-
Marek GJ, Aghajanian GK. Marek GJ, et al. J Pharmacol Exp Ther. 1996 Sep;278(3):1373-82. J Pharmacol Exp Ther. 1996. PMID: 8819525
-
Hungen KV, Roberts S, Hill DF. Hungen KV, et al. Brain Res. 1975 Aug 22;94(1):57-66. doi: 10.1016/0006-8993(75)90876-8. Brain Res. 1975. PMID: 238721
-
Acute effects of lysergic acid diethylamide (LSD) on resting brain function.
Müller F, Borgwardt S. Müller F, et al. Swiss Med Wkly. 2019 Sep 30;149:w20124. doi: 10.4414/smw.2019.20124. eCollection 2019 Sep 23. Swiss Med Wkly. 2019. PMID: 31568558 Review.
Cited by
-
Hallucinogenic Persisting Perception Disorder: A Case Series and Review of the Literature.
Ford H, Fraser CL, Solly E, Clough M, Fielding J, White O, Van Der Walt A. Ford H, et al. Front Neurol. 2022 May 6;13:878609. doi: 10.3389/fneur.2022.878609. eCollection 2022. Front Neurol. 2022. PMID: 35599738 Free PMC article.
-
Systematic review and rationale of using psychedelics in the treatment of cannabis use disorder.
Phan AN, Terry GE. Phan AN, et al. Front Psychiatry. 2023 Jun 26;14:1144276. doi: 10.3389/fpsyt.2023.1144276. eCollection 2023. Front Psychiatry. 2023. PMID: 37435402 Free PMC article.
-
Pathological Delta Oscillations in Hallucinogen Persisting Perception Disorder: A Case Report.
Haslacher D, Novkovic N, Buthut M, Heinz A, Soekadar SR. Haslacher D, et al. Front Psychiatry. 2022 Mar 24;13:867314. doi: 10.3389/fpsyt.2022.867314. eCollection 2022. Front Psychiatry. 2022. PMID: 35401281 Free PMC article.
-
Recreational drug misuse: issues for the cardiologist.
Ghuran A, Nolan J. Ghuran A, et al. Heart. 2000 Jun;83(6):627-33. doi: 10.1136/heart.83.6.627. Heart. 2000. PMID: 10814617 Free PMC article. Review. No abstract available.
-
Use and abuse of dissociative and psychedelic drugs in adolescence.
Bates MLS, Trujillo KA. Bates MLS, et al. Pharmacol Biochem Behav. 2021 Apr;203:173129. doi: 10.1016/j.pbb.2021.173129. Epub 2021 Jan 28. Pharmacol Biochem Behav. 2021. PMID: 33515586 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical