Another case of t(17;22)(q22;q13) in an infantile dermatofibrosarcoma protuberans - PubMed

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Another case of t(17;22)(q22;q13) in an infantile dermatofibrosarcoma protuberans

F Pedeutour et al. Cancer Genet Cytogenet. 1996.

Abstract

We have identified a new dermatofibrosarcoma protuberans (DP) case with a t(17;22) (q22;q13) occurring in a child. The translocation was substantiated by the presence of one or two copies of the sole der(22)t(17;22). This rearrangement added to two normal chromosomes 17 and one or two chromosomes 22, resulted in trisomy 22cen-q13 and trisomy (or tetrasomy) 17q22-25. This observation confirms the specificity of the association of DP with the t(17;22) found together with extra copies of the der(22)t(17;22). It also points out a possible prevalence of translocation rather than rings in DP of the childhood disease.

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