[Pseudo-allergies are due to histamine intolerance] - PubMed

[Article in German]

Affiliations

• PMID: 9012205

Review

[Pseudo-allergies are due to histamine intolerance]

[Article in German]

M Götz. Wien Med Wochenschr. 1996.

Abstract

Numerous undesirable reactions to alcoholic beverages, foods, drugs and other substances are characterized by allergy-like signs and symptoms and yet show unambiguously negative allergy test results. Such persons should be assessed for evidence of histamine intolerance caused by histamine overload and/or diamine oxidase deficiency. Diamine oxidase is the main histamine degrading enzyme with a predominantly gut activity. This would explain why nutritional allergies are often primarily suspected. The clinical evidence for histamine intolerance is based on chronic headache, diarrhoea, vomiting, flush, urticaria, asthma-like symptoms, rhinitis and others. Histamine restricted food, supported if necessary by H1 antihistamine blockade are simple but highly efficacious measures as shown by us in large patient groups. Intolerance to red wine probably is the most outstanding clinical characteristic and a directed question must be included into any allergy history in order to avoid missing a very major diagnostic spectrum with good therapeutic maneuverability.

Similar articles

• Histamine-free diet: treatment of choice for histamine-induced food intolerance and supporting treatment for chronic headaches.

  Wantke F, Götz M, Jarisch R. Wantke F, et al. Clin Exp Allergy. 1993 Dec;23(12):982-5. doi: 10.1111/j.1365-2222.1993.tb00287.x. Clin Exp Allergy. 1993. PMID: 10779289 Clinical Trial.

• [The histamine-free diet].

  Wantke F, Götz M, Jarisch R. Wantke F, et al. Hautarzt. 1993 Aug;44(8):512-6. Hautarzt. 1993. PMID: 8376104 German.

• [Intolerance reaction caused by biogenic amines. A separate disease entity?].

  Bischoff SC, Manns MP. Bischoff SC, et al. Internist (Berl). 1998 Mar;39(3):317-8. Internist (Berl). 1998. PMID: 9561456 German. No abstract available.

• Histamine and histamine intolerance.

  Maintz L, Novak N. Maintz L, et al. Am J Clin Nutr. 2007 May;85(5):1185-96. doi: 10.1093/ajcn/85.5.1185. Am J Clin Nutr. 2007. PMID: 17490952 Review.

• Wine and headache.

  Jarisch R, Wantke F. Jarisch R, et al. Int Arch Allergy Immunol. 1996 May;110(1):7-12. doi: 10.1159/000237304. Int Arch Allergy Immunol. 1996. PMID: 8645981 Review.

Cited by

• [Alimentary trigger factors that provoke migraine and tension-type headache].

  Holzhammer J, Wöber C. Holzhammer J, et al. Schmerz. 2006 Apr;20(2):151-9. doi: 10.1007/s00482-005-0390-2. Schmerz. 2006. PMID: 15806385 German.

• Vegetal diamine oxidase alleviates histamine-induced contraction of colonic muscles.

  Neree AT, Soret R, Marcocci L, Pietrangeli P, Pilon N, Mateescu MA. Neree AT, et al. Sci Rep. 2020 Dec 9;10(1):21563. doi: 10.1038/s41598-020-78134-3. Sci Rep. 2020. PMID: 33299054 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information