Zika without symptoms in returning travellers: What are the implications?
“…S1A), and thus likely targets a discontinuous or conformational epitope displayed on the surface of ZIKV NS1. Because ZKA35 mAb was isolated from an individual infected with ZIKV on a trip to Guatemala and El Salvador in November 2015 (19), it is plausible this antibody was elicited by NS1 antigen from an American ZIKV strain. However, it binds equally well to recombinant NS1 from a 2016 Suriname ZIKV strain, as well as from the prototype Ugandan strain MR766 (Fig.…”
Section: Discussionmentioning
“…It is transmitted by mosquitoes and through sexual intercourse ( 3 ). Most persons infected with Zika virus are asymptomatic or experience mild symptoms ( 4 ). However, in a pregnant woman, infection may cause severe pregnancy and birth complications, most notably microcephaly in children infected in utero ( 5 – 7 ).…”
mentioning
“…All travelers, and especially pregnant women, should take measures to avoid insect bites and arboviral infections (3,47,48). Zika virus-infected people may appear healthy and asymptomatic although they have viremia and may shed the virus (49). To avoid transmission of Zika virus via blood donations, blood banks will have to explore the travel anamnesis of their donors (49).…”
Section: Prophylaxismentioning
“…Zika virus-infected people may appear healthy and asymptomatic although they have viremia and may shed the virus (49). To avoid transmission of Zika virus via blood donations, blood banks will have to explore the travel anamnesis of their donors (49).…”
Section: Prophylaxismentioning