miRNA expression profiling of cerebrospinal fluid in patients with aneurysmal subarachnoid hemorrhage

“…Recently, studies of miRNAs in serum and cerebrospinal fluid identified biomarkers associated with occurrence of SAH, including miR‐92a, let‐7b, miR‐204‐5p, miR‐223‐3p, miR‐337‐5p, miR‐451a, miR‐489, miR‐508‐3p, miR‐514‐3p, miR‐516‐5p, miR‐548, miR‐599, miR‐937, miR‐1224‐3p and miR‐1301 . Our previous genomewide serum miRNA expression profiling also suggested that miR‐132‐3p and miR‐324‐3p could be potential biomarkers for SAH . Styllis and others investigated cerebrospinal fluid miRNAs in 10 SAH patients with and 10 without cerebral vasospasm and identified miR‐27a‐3p, miR‐516a‐5p, miR‐566, and miR‐1197 as potential biomarkers for cerebral vasospasm but not DCI .…”