How to: Establish and run a stool bank
“…As discussed above, there is an absence of published studies to support the recommendations in this section (although the experience of setting up a nationwide stool bank has recently been reported from The Netherlands129). This section is therefore based on the working group’s expert opinion and experience of developing FMT services.…”
Section: Basic Requirements For Implementing a Fmt Servicementioning
“…The working group discussed a recent retrospective study demonstrating that exposure to non-anti-CDI antimicrobials within 8 weeks of FMT is associated with an approximate threefold risk of FMT failure (n=8/29 failures with antibiotic exposure vs 36/320 failures without antibiotic exposure) 128. Similarly, the experience of the large pan-Netherlands stool bank129 was that ~50% of their failures of FMT in the treatment of recurrent CDI occurred in patients who had received antibiotics within 1 month of their FMT. For patients requiring long term antibiotics, the working group’s expert opinion was that such patients should still be eligible for FMT, but that the regimen for the use of non-anti-CDI antibiotics should be decided on a case by case basis, based on factors including response to FMT and/or strength of indication of antibiotics.…”
Section: Rationale For Recommendationsmentioning
“…Given the potential implications of transferring pathogenic microorganisms, a cautious approach to screening has been applied in most studies and guidelines . This is analogous with the procedures employed by blood service organizations and emphasizes the need for voluntary (i.e., unpaid) donations.…”
Section: Infrastructure Of An Fmt Servicementioning
“…Stool banks should only provide access to screened stool that can be traced to the donor and for documenting adverse events in the short, medium and long term. [12] This division provides a practical organisational structure and clarifies both the tasks and the necessary personnel to maintain an operational stool bank nationally or regionally.…”
Section: Editorialmentioning