Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout - Virology Journal
- ️Kümmerer, Beate Mareike
- ️Mon Jul 15 2013
Table 1 Neutralizing antibody titers (NT 50 )
Virus-NTa | VRP-NT (24 well)b | VRP-NT (96 well)b | ||||
|---|---|---|---|---|---|---|
mAb/ Serum | NT 50 c | (95% CI) e | NT 50 d | (95% CI) | NT 50 d | (95% CI) |
D3.62 | 16256 | (13465 – 19731) | 58306 | (45196 – 79754) | 26885 | (22799 – 32054) |
1753/06 | 5978 | (4882 – 7350) | 16203 | (12911 – 20881) | 26314 | (21004 – 34401) |
662/06 | 3582 | (2581 – 5061) | 13437 | (11819 – 15382) | 18743 | (15050 – 24194) |
575/06 | 1375 | (615 – 2183) | 4511 | (3590 – 5662) | 10911 | (7743–15876) |
- a Neutralization assay performed with virus particles (plaque assay).
- b Neutralization assay performed with virus replicon particles (Gluc assay).
- c NT50 values were determined via probit analysis using the data set of Figure 5B.
- d NT50 values were determined via probit analysis using the data sets of Figure 5C.
- e 95% confidence interval.