index

Myosin

Structure

Size and shape of the myosin molecule

Myosin light chains

Review

Function

Myosin-actin binding

ATPase activity of myosin

Separate actin-binding and ATPase sites of myosin

Intermediates of the ATP hydrolysis

ATPase activity of myosin and speed of muscle shortening

Myosin heavy chains

Three dimensional structure of subfragment 1

Structure-function relationship in myosin

Assembly

Myosin filament

Muscle fibers, myofibrils

Localization of myosin in the structure of muscle

References

Actin

The two forms of actin

Actin-myosin binding

Three dimensional structure of actin

The intersubunit contacts in the F-actin filaments

Localization of actin in the structure of muscle

Structure of the thin filament

References

Actin-Myosin Interaction

Structural model

Contact sites

Lever arm model

X-ray diffraction and electron microscopy of muscle

In vitro motility assay

References