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History
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Intranasal treatment of vitamin B12 deficiency in children - European Journal of Pediatrics
Vitamin B12 deficiency is traditionally treated with intramuscular injections of cobalamin, which are stressful events for children. In adults, studies have shown adequate absorption of intranasally administered vitamin B12. To date, data concerning efficacy of intranasal administration of vitamin B12 in children are lacking. We report on ten cases of children with vitamin B12 deficiency who were successfully treated with intranasal administration of a spray containing hydroxocobalamin. The mean baseline vitamin B12 concentration increased from 126.3 pmol/l (SD 55.4) to 1914.7 pmol/l (SD 1509.7). No side effects were reported.Conclusion: In children, intranasal application of vitamin B12 seems a safe and effective alternative to intramuscular injections, leading to higher compliance and less burden to patients.What is Known:• Children with vitamin B12deficiency are traditionally treated with intramuscular cobalamin injections, which are costly and painful.• Studies in adults showed that intranasal application of hydroxocobalamin leads to normalisation of vitamin B12levels.What is New:• The intranasal application of vitamin B12resulted in a substantial increase of the mean baseline vitamin B12levels without any side effect.• These data encourage a systematic evaluation of intranasal treatment of vitamin B12deficiency in order to define safety, optimal dosage and administration frequency.
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Ein neues Diaphanoskop - The Science of Nature
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From a Native Daughter
Since its publication in 1993, From a Native Daughter, a provocative, well-reasoned attack against the rampant abuse of Native Hawaiian rights, institutional racism, and gender discrimination, has generated heated debates in Hawai'i and throughout the world. This 1999 revised work includes material that builds on issues and concerns raised in the first edition: Native Hawaiian student organizing at the University of Hawai'i; the master plan of the Native Hawaiian self-governing organization Ka Lahui Hawai'i and its platform on the four political arenas of sovereignty; the 1989 Hawai'i declaration of the Hawai'i ecumenical coalition on tourism; and a typology on racism and imperialism. Brief introductions to each of the previously published essays brings them up to date and situates them in the current Native Hawaiian rights discussion.
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Breaking 104 Bit WEP in Less Than 60 Seconds
We demonstrate an active attack on the WEP protocol that is able to recover a 104-bit WEP key using less than 40,000 frames with a success probability of 50%. In order to succeed in 95% of all cases, 85,000 packets are needed. The IV of these packets can be randomly chosen. This is an improvement in the number of required frames by more than an order of magnitude over the best known key-recovery attacks for WEP. On a IEEE 802.11g network, the number of frames required can be obtained by re-injection in less than a minute. The required computational effort is approximately 220 RC4 key setups, which on current desktop and laptop CPUs is negligible.
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Microsoft Security Bulletin MS12-006 - Important
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