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CDC - NIOSH Pocket Guide to Chemical Hazards - Acrylamide

Synonyms & Trade Names

Acrylamide monomer, Acrylic amide, Propenamide, 2-Propenamide

Physical Description

White crystalline, odorless solid.

Combustible Solid (may also be dissolved in flammable liquids).

Incompatibilities & Reactivities

Strong oxidizers [Note: May polymerize violently upon melting.]

Exposure Routes

inhalation, skin absorption, ingestion, skin and/or eye contact

Symptoms

irritation eyes, skin; ataxia, numb limbs, paresthesia; muscle weak; absent deep tendon reflex; hand sweating; lassitude (weakness, exhaustion), drowsiness; reproductive effects; [potential occupational carcinogen]

Target Organs

Eyes, skin, central nervous system, peripheral nervous system, reproductive system

Cancer Site

[in animals: tumors of the lungs, testes, thyroid & adrenal glands]

Personal Protection/Sanitation

(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated/Daily
Remove:When wet or contaminated
Change:Daily
Provide:Eyewash, Quick drench

First Aid

(See procedures)
Eye:Irrigate immediately
Skin:Water flush immediately
Breathing:Respiratory support
Swallow:Medical attention immediately

Respirator Recommendations

NIOSH

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection