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KEGG ORTHOLOGY: K10150

Entry

K10150                      KO                                     

Symbol

cysO

Name

cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]

Pathway
map00260  Glycine, serine and threonine metabolism
map00270  Cysteine and methionine metabolism
map00670  One carbon pool by folate
map00920  Sulfur metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
Module
M00035  Methionine degradation
M00338  Cysteine biosynthesis, homocysteine + serine => cysteine
Reaction
R00891  L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
R00897  O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
R01290  L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)
R03601  O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
R04859  O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming)
R04942  L-serine hydro-lyase (adding homocysteine)
R07274  O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
Brite

KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00920 Sulfur metabolism
    K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
   00270 Cysteine and methionine metabolism
    K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.47  cysteine synthase
     K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
    2.5.1.65  O-phosphoserine sulfhydrylase
     K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.22  cystathionine beta-synthase
     K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase

Other DBs
GO: 0004124 0033847 0004122
Genes
APE: APE_1586(cysK)
ACJ: ACAM_0997(cysK)
DFD: Desfe_0630
DMU: Desmu_0644
TAG: Tagg_1314
IAG: Igag_1783
THG: TCELL_0171
HBU: Hbut_1585
PFM: Pyrfu_1108
PDL: Pyrde_0768
PABI: PABY_05110
PIS: Pisl_1761
TPE: Tpen_1605
ASC: ASAC_0793
ACIA: SE86_05800
CCAI: NAS2_0810
 » show all
Reference
  Authors

Mino K, Ishikawa K

  Title

Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.

  Journal

J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003

  Sequence

[ape:APE_1586]

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