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KEGG REACTION: R00897

Entry

R00897                      Reaction                               

Name

O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase;
O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)

Definition

O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate

Equation
Reaction class
RC00020  C00033_C00979
RC02814  C00097_C00283
RC02821  C00097_C00979
Enzyme

2.5.1.47        2.5.1.65

Pathway
rn00270  Cysteine and methionine metabolism
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01230  Biosynthesis of amino acids
rn01320  Sulfur cycle
Module
M00021  Cysteine biosynthesis, serine => cysteine
Brite

Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.47
     R00897  O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate
    2.5.1.65
     R00897  O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate

Orthology
K01738  cysteine synthase [EC:2.5.1.47]
K10150  cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
K13034  L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9]
K17069  O-acetylhomoserine/O-acetylserine sulfhydrylase [EC:2.5.1.49 2.5.1.47]
Other DBs
RHEA: 14832
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