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KEGG REACTION: R01283

Entry

R01283 Reaction

Name

L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)

Definition

L-Homocysteine + H2O <=> Hydrogen sulfide + Ammonia + 2-Oxobutanoate

Equation

C00155 + C00001 <=> C00283 + C00014 + C00109

Comment

multi-step reaction (see R08633+R08637)

Reaction class

RC00487

C00109_C00155

RC02814

C00155_C00283

Enzyme

4.4.1.2

Pathway

rn00920

Sulfur metabolism

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
4. Lyase reactions
  4.4  Carbon-sulfur lyases
   4.4.1  Carbon-sulfur lyases (only sub-subclass identified to date)
    4.4.1.2
     R01283  L-Homocysteine + H2O <=> Hydrogen sulfide + Ammonia + 2-Oxobutanoate

Orthology

K17217

cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]

Other DBs

RHEA:

14504

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