Supplementary Figure 1: Schematic comparison of a nucleotide- and a protein assembly. | Nature Methods
On top is the final protein assembly followed by the stacked overlapping protein reads. The small gray section highlights the multiple protein sequence alignment of the overlapping reads and below the respective nucleotide alignment. Less ambiguity is visible on the protein level due to conservative mutations (mutations with similar biochemical properties) compared to the nucleotide level, resulting in an assembly that is more robust to microdiversity in the population.