RecName: Full=Ubiquitin thioesterase OTU1; AltName: Full=DUBA-8; AltNa - Protein - NCBI

Analyze this sequence

• Run BLAST

  Find regions of similarity between this sequence and other sequences using BLAST.

• Identify Conserved Domains

  View conserved domains detected in this protein sequence using CD-search.

• Highlight Sequence Features

  Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...

• Find in this Sequence

  Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Articles about the YOD1 gene

• Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer. [BMB Rep. 2017]

  Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer.

  BMB Rep. 2017 Jun; 50(6):281-282.

• Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein. [Biochem Biophys Res Commun. 2023]

  Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein.

  Park SS, Do HA, Park HB, Choi HS, Baek KH. Biochem Biophys Res Commun. 2023 Feb 19; 645:124-131. Epub 2023 Jan 13.

• Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells. [Acta Pharm Sin B. 2022]

  Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells.

  Shao X, Chen Y, Wang W, Du W, Zhang X, Cai M, Bing S, Cao J, Xu X, Yang B, et al. Acta Pharm Sin B. 2022 Apr; 12(4):1856-1870. Epub 2021 Oct 23.

See all...

Reference sequence information

• RefSeq protein isoforms

  See 4 reference sequence protein isoforms for the YOD1 gene.

Related information

• PubMed

  PubMed articles cited by protein sequence record

• Taxonomy

  Taxonomy sequences associated with protein record

• BioSystems

  BioSystems

• CDD Search Results

  Display conserved domains within a protein

• Conserved Domains (Concise)

  Link to a concise list of conserved domains in a protein

• Conserved Domains (Full)

  Link to conserved domains within a protein

• Domain Relatives

  Display proteins with similar conserved domain architecture

• Full text in PMC

  Free full text articles in PMC

• Gene

  Link to related Genes

• Identical Structures

  3D structures for identical protein sequences

• OMIM

  OMIM records associated with protein sequence

• Protein (RefSeq)

  Protein gi (UniProtKB) to protein gi (refseq)

• PubMed (Weighted)

  Links to pubmed

• Related Structures (List)

  List of related structures

LinkOut to external resources

• Q5VVQ6 [Domain Mapping of Disease Mut...]

  Q5VVQ6

  Domain Mapping of Disease Mutations

• Transcript/Protein Information [PANTHER Classification System]

  Transcript/Protein Information

  PANTHER Classification System

• Reactome [Reactome]

  Reactome

• reagents [ExactAntigen/Labome]

  reagents

  ExactAntigen/Labome