| John Cleese | ... Cat R. Waul (voice) |
| Dom DeLuise | ... Tiger (voice) |
| Phillip Glasser | ... Fievel (voice) |
| Amy Irving | ... Miss Kitty (voice) |
|
| Jon Lovitz | ... Chula (voice) |
| Cathy Cavadini | ... Tanya (voice) |
| Nehemiah Persoff | ... Papa (voice) |
| Erica Yohn | ... Mama (voice) |
|
| and |
| Jimmy Stewart | ... Wylie Burp (voice) |
|
| Additional Voices |
| Jack Angel | ... Additional Voices (voice) |
| Mickie McGowan | ... Additional Voices (voice) |
| Fausto Bara | ... Additional Voices (voice) |
| Larry Moss | ... Additional Voices (voice) |
| Vanna Bonta | ... Additional Voices (voice) |
| Nigel Pegram | ... Additional Voices (voice) |
| Philip Clarke | ... Additional Voices (voice) |
| Patrick Pinney | ... Additional Voices (voice) |
| Jennifer Darling | ... Additional Voices (voice) |
| Lisa Raggio | ... Additional Voices (voice) |
| Annie Holliday | ... Additional Voices (voice) |
| Lawrence Steffan | ... Additional Voices (voice) |
| Sherry Lynn | ... Additional Voices (voice) |
| David Tate | ... Additional Voices (voice) |
| Lev Mailer | ... Additional Voices (voice) |
| Robert Watts | ... Additional Voices (voice) |