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Nobel Prize in Chemistry 1989

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Thomas R. Cech

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Thomas R. Cech
Nobel Prize in Chemistry 1989

Born: 8 December 1947, Chicago, IL, USA

Affiliation at the time of the award: University of Colorado, Boulder, CO, USA

Prize motivation: “for their discovery of catalytic properties of RNA”

Prize share: 1/2

Work

Enzymes are substances that speed up the chemical processes in organisms' cells without being consumed. It was long thought that all enzymes were proteins. Sidney Altman and Thomas Cech demonstrated that RNA can also function as an enzyme. In 1982, Cech studied the way RNA molecules from the microorganism Tetrahymena thermophila split into fragments. He discovered that RNA molecules inside a test tube split themselves using a complicated chemical reaction, despite the absence of a protein.

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Six prizes were awarded for achievements that have conferred the greatest benefit to humankind. The 12 laureates' work and discoveries range from proteins' structures and machine learning to fighting for a world free of nuclear weapons.

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