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Ethylene thiourea - Wikiwand

Ethylene thiourea (ETU) is an organosulfur compound with the formula C3H6N2S. It is an example of an N,N-disubstituted thiourea. It is a white solid. It is synthesized by treating ethylenediamine with carbon disulfide.[3]

Quick Facts Names, Identifiers ...

Ethylene thiourea
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Names
Preferred IUPAC name

Imidazolidine-2-thione

Other names

1,3-Ethylene-2-thiourea, N,N-Ethylenethiourea

Identifiers

3D model (JSmol)
ChemSpider
ECHA InfoCard 100.002.280
UNII

  • InChI=1S/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6)

    Key: PDQAZBWRQCGBEV-UHFFFAOYSA-N

  • InChI=1/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6)

    Key: PDQAZBWRQCGBEV-UHFFFAOYAQ

  • C1CNC(=S)N1

Properties
C3H6N2S
Molar mass 102.16 g·mol−1
Appearance White solid
Odor Faint, amine-like
Melting point 203 °C (397 °F; 476 K)
Boiling point 347.18 °C (656.92 °F; 620.33 K)
2% (30 °C)[1]
Vapor pressure 16 mmHg (20 °C)[1]
Hazards
Occupational safety and health (OHS/OSH):

Main hazards

 combustible[1]
Flash point 252.2 °C (486.0 °F; 525.3 K)
Lethal dose or concentration (LD, LC):
1832 mg/kg (oral, rat)[2]
NIOSH (US health exposure limits):

PEL (Permissible)

 None[1]

REL (Recommended)

 Ca Use encapsulated form.[1]

IDLH (Immediate danger)

 Ca [N.D.][1]

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

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Ethylene thioureas are an excellent accelerant of vulcanization of neoprene rubbers. In commercial use is the N,N'-diphenylethylenethiourea. Due to reproductive toxicity, carcinogenicity, and mutagenicity, alternatives are being sought to the ethylenethioureas. One candidate replacement is N-methyl-2-thiazolidinethione.[4]

Ethylene thiourea can be used as a biomarker of exposure to ethylenebisdithiocarbamates (EBDTCs), which are frequently employed as fungicides in agriculture, mainly on fruits, vegetables and ornamental plants.[5]

EPA (United States Environmental Protection Agency) has classified ethylene thiourea as a Group B2, probable human carcinogen.[6] Ethylene thiourea has been shown to be a potent teratogen (causes birth defects) in rats orally or dermally exposed.