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New concept of urban green management - Clean Technologies and Environmental Policy

Many cities face a long-term surplus of grass cuttings. Its management is usually financially demanding once many of the up to date technologies require high acquisition as well as variable costs. It was verified in a commercial scale if the newly proposed concept of anaerobic fermentation followed by continuous pyrolysis is technically and economically feasible to manage macerated cutting of urban green in a commercial scale. Design of the concept is thoroughly described, documented in figures, and biochemically analyzed in detail. Assessment of the concept shows that subsequent pyrolysis of the anaerobically fermented residue allows among biogas to produce also high-quality charcoal. It was proved that the proposed solution improves the overall economy. In addition, it may be assumed that this applied research is consistent with previous theoretical assumptions stating that any kind of aerobic or anaerobic fermentation increases the heating value of the charcoal obtained.

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Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer - Journal of Cancer Research and Clinical Oncology

Background and objectives Enhancer of zeste 2 (EZH2), embryonic ectoderm development (EED), and suppressor of zeste 12 homolog (SUZ12), the key component of polycomb repressive complex 2, are of great importance in human cancer pathogenesis. This study was designed to investigate the clinical and prognostic significances of EZH2, EED and SUZ12 in colorectal cancer (CRC) patients. Methods The expression of EZH2, EED and SUZ12 mRNA was evaluated in 82 primary CRC and paired non-cancerous mucosa samples by qRT-PCR. Results We found that overall EZH2, EED and SUZ12 mRNA expression in the CRC tissues was significantly increased than in the non-cancerous tissue (p < 0.05). Increased EZH2, EED and SUZ12 mRNA expression was directly correlated with primary tumor size, regional lymph node metastases, distant metastasis and AJCC stage. Furthermore, CRC patients with higher level of EED, SUZ12 or EZH2 showed a worse disease-free survival (DFS) (p < 0.01). In multivariate analysis, the increased EZH2 expression may be a risk factor for the patients’ 3-year DFS (HR 2.517; 95 % CI 1.104, 5.736; p = 0.028). Furthermore, the k-means cluster analysis showed that high mRNA expression of EED, SUZ12 and EZH2 was significantly correlated with the aggressive clinical behavior and poor prognosis. Conclusions High expression of EED, SUZ12 and EZH2 might contribute to the CRC development/progression.